Recombinant Rabbit IFN gamma

• Cat.No.: IFNg-28R
• Product Overview: Rabbit IFN gamma was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.

Specification

• Description: Interferon-gamma (IFN-gamma) is a dimerized soluble cytokine that is the only member of the type II class of interferons. This interferon was originally called macrophage-activating factor, a term now used to describe a larger family of proteins to which IFN-gamma belongs. IFN-gamma, or type II interferon, is a cytokine that is critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Aberrant IFN-gamma expression is associated with a number of autoinflammatory and autoimmune diseases. The importance of IFN-gamma in the immune system stems in part from its ability to inhibit viral replication directly, but, most important, derives from its immunostimulatory and immunomodulatory effects. IFN-gamma is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.
• Source: Yeast
• Species: Rabbit
• Form: Lyophilized
• Molecular Mass: 16.9 kDa
• AA Sequence: QDTLTRETEHLKAYLKANTSDVANG GPLFLNILRNWKEESDNKIIQSQIV S FYFKLFDNLKDHEVIKKSMESIKED IFVKFFNSNLTKMDDFQNL TRISVDDRLVQRKAVSELSNVLNFL SPKSNLKKRKRSQTLFRG RRASKY (144)
• Applications: The rabbit IFN gamma protein can be used in cell culture, as a IFN gamma ELISA Standard, and as a Western Blot Control.
• Storage: -20 C
• Tag: Non

Gene Information

• Gene Name: IFNG interferon, gamma [ Oryctolagus cuniculus ]
• Official Symbol: IFNg
• Synonyms: IFNG; interferon, gamma; interferon gamma; IFN gamma; IFN-gamma
• Gene ID: 100008602
• mRNA Refseq: NM_001081991
• Protein Refseq: NP_001075460

Reviews

12/17/2022

It is analyzed by X-ray crystallography or other crystallization techniques and has good crystallization properties.

06/10/2022

Easy to attach to the surface of cells or materials.

04/02/2022

IFNG products have a complete range of specifications for experimental designs of different sizes and needs.

Q&As

What is the role of IFNG in tumor immunotherapy?

IFNG plays an important role in tumor immunotherapy, which can activate the immune response of tumor cells, promote apoptosis of tumor cells and inhibit the proliferation of tumor cells.

What is the current progress in drug development for IFNG?

The development of drugs for IFNG is currently in clinical trials, including monoclonal antibodies against IFNG receptors and inhibitors against IFNG signaling pathways.

How is IFNG related to muscle wasting?

Studies have shown that IFNG can inhibit the occurrence of muscle atrophy, but the specific mechanism is not clear.

How can IFNG be used as a biomarker in clinical practice?

In clinical practice, the expression level of IFNG can be measured to predict the progression and prognosis of the disease, and to guide the choice of treatment regimen.

Are there other coding variants in the IFNG gene?

Yes, there are other coding variants in the IFNG gene that may have different functions and expression patterns.

Is the expression of IFNG affected by environmental factors?

Such as nutritional status, inflammation levels, etc. Yes, the expression of IFNG is affected by environmental factors, such as nutritional status, inflammation level, etc.