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Recombinant Rat ABCC5 Protein

Cat.No. : ABCC5-406R
Product Overview : Recombinant Rat ABCC5 full length or partial length protein was expressed.
  • Specification
  • Gene Information
  • Related Products
Source : Mammalian Cells
Species : Rat
Tag : His
Form : Liquid or lyophilized powder
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : >80%
Notes : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Storage : Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Storage Buffer : PBS buffer
Gene Name : Abcc5 ATP-binding cassette, subfamily C (CFTR/MRP), member 5 [ Rattus norvegicus ]
Official Symbol : ABCC5
Gene ID : 116721
mRNA Refseq : NM_053924.1
Protein Refseq : NP_446376.1
MIM :
UniProt ID : Q9QYM0

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (16)

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What are the inhibitors of ABCC5? 08/03/2022

Progesterone, testosterone and their analogues

What are the transporters that lead to sorafenib resistance? 05/06/2022

No clear research results. But the down-regulation of ABCC5 expression could significantly reduce the resistance of sorafenib to HCC cells.

Which drug resistant proteins are increased in breast cancer cells? 04/16/2022

The expression levels of ABCC2, ABCC4, ABCC5, and ABCG2 significantly increased in the pan-resistant cell line, and the ABCC5 level in the MCF-7-ADR cell line was 5.21 times higher than that in the control group.

What ions can MRP5 transport? 03/12/2022

MRP4 (ABCC4) and MRP5 (ABCC5) are organic anion transporters.

Does ABCC5 abnormality cause glaucoma? 01/29/2022

PLEKHA7, ABCC5, and KALRN have been identified as susceptible genetic markers related to glaucoma.

Which abc proteins play a role in liver cancer cells? 12/19/2021

There is no clear result now. Some research show that ABCC5 was differently expressed and strongly related to the pathological stage of LIHC.

Does inhibition of ABCC5 play a role in paclitaxel resistance? 06/13/2021

Not in all the tumors. Small molecular inhibitors of FOXM1 or ABCC5 have the potential to overcome paclitaxel chemoresistance in nasopharyngeal carcinoma patients

Can ABCC5 lose weight? 05/19/2021

The role of ABCC5 in diabetes and obesity is unknown. ABCC5 protein expression levels are inversely related to fat mass and appear to play a role in the regulation of GLP-1 secretion from enteroendocrine cells.

Which mutation of ABCC5 causes diabetes? 05/07/2021

No result shows that ABCC5 mutation will lead to diabetes. Research shows that ABCC5 transporter is a new type 2 diabetes susceptibility gene

Whether ABCC5 can regulate prostate cancer progression? 07/19/2020

Some study demonstrated that ABCC5 knockdown significantly inhibits PCa cell proliferation, migration, and invasion in vitro and suppresses tumor growth and metastasis in vivo.

Does ABCC5 have a crystal structure? 03/04/2020

It has not yet been reported.

What are the polymorphisms of ABCC5? What has an impact on drug resistance? 05/19/2019

There are many polymorphisms on ABCC5, such as, ABCC5 g.+7161G>A (rs1533682),g.+7161AA,g.+7161GG,g.-1679T>A, c.2T>C, c.343A>G, and c.1573G>A.

Can ABCC5 be used as a cancer biomarker? 05/16/2019

More research data are needed to prove.A study shows that the expression of ABCC5 was up-regulated in HCC and was associated with poor prognosis.

What is the organizational distribution of MRP5? 05/03/2019

The protein is widely expressed in various tissues, with particularly high levels observed in the liver, kidney, and prostate.

Can you express ABCC5 mutant protein? 07/13/2018

Yes, please contact us for more information.

In which tissues of zebrafish is ABCC5 highly expressed 09/19/2016

In adults, zebrafish abcc5 is extensively expressed, at higher levels in testis, brain, eye, ovary, intestine and kidney, but at relatively lower levels in gill, liver, heart and muscle.

Customer Reviews (3)

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Reviews
01/29/2023

    Reasonable price and high quality

    03/09/2018

      It is cost-effective to buy when promoting

      08/14/2017

        There are many expression systems to choose from

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