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Recombinant Rat AHRR Protein

Cat.No. : AHRR-573R
Product Overview : Recombinant Rat AHRR full length or partial length protein was expressed.
  • Specification
  • Gene Information
  • Related Products
Source : Mammalian Cells
Species : Rat
Tag : His
Form : Liquid or lyophilized powder
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : >80%
Notes : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Storage : Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Storage Buffer : PBS buffer
Gene Name : Ahrr aryl-hydrocarbon receptor repressor [ Rattus norvegicus ]
Official Symbol : AHRR
Gene ID : 498999
mRNA Refseq : NM_001024285.1
Protein Refseq : NP_001019456.1
MIM :
UniProt ID : Q75NT5

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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Discuss the impact of AHRR polymorphisms on its function and their association with disease susceptibility? 08/28/2022

Genetic variations in AHRR can lead to altered protein function and influence individual susceptibility to diseases influenced by the AHR signaling pathway, such as cancer and immune-related disorders.

How does AHRR affect the susceptibility to environmental carcinogens and toxicants? 07/16/2022

AHRR expression can influence an individual's sensitivity to environmental carcinogens and toxicants by modulating AHR activity and downstream gene expression.

How does AHRR expression vary in different tissues and cell types, and what factors influence this variability? 12/12/2021

AHRR expression levels can vary among tissues and cell types, depending on the local microenvironment, exposure to specific ligands, and tissue-specific transcriptional regulators.

What is the structural organization of the AHRR protein, and how does it interact with the AHR? 05/22/2021

AHRR contains domains that enable its interaction with AHR, such as bHLH (basic helix-loop-helix) and PAS (Per-Arnt-Sim) domains, facilitating the formation of inhibitory complexes with AHR.

Describe the function of AHRR in the AHR signaling pathway? 08/09/2020

AHRR acts as a negative regulator of the AHR signaling pathway, inhibiting AHR-mediated gene transcription in response to ligand activation.

What are the molecular mechanisms through which AHRR suppresses AHR-dependent gene expression? 03/02/2020

AHRR competes with AHR for binding to the same target genes, effectively blocking AHR-mediated transcription and inhibiting the expression of AHR-responsive genes.

Describe the involvement of AHRR in inflammatory processes and immune responses? 06/27/2019

AHRR is implicated in modulating inflammatory responses and immune cell differentiation, affecting the balance between pro-inflammatory and anti-inflammatory signals.

How is AHRR expression regulated, and what are the factors that control its levels in cells? 01/23/2019

AHRR expression can be induced by various environmental stimuli, such as exposure to AHR ligands and other stressors. Transcription factors and epigenetic modifications can regulate AHRR gene expression.

Discuss the role of AHRR in xenobiotic metabolism and detoxification? 10/04/2018

AHRR plays a crucial role in regulating the expression of genes involved in xenobiotic metabolism and detoxification, contributing to the body's defense against environmental toxins.

How does AHRR participate in the regulation of circadian rhythm and metabolic homeostasis? 05/25/2018

AHRR is involved in circadian rhythm regulation and contributes to metabolic homeostasis by influencing the expression of clock genes and metabolic regulators.

Customer Reviews (5)

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Reviews
06/26/2022

    Results were spot-on using their stratified products.

    12/01/2021

      Friendly service, and the stratified protein delivered.

      09/11/2020

        The protein enhanced our research.

        04/19/2019

          Received excellent support and a reliable products.

          12/03/2018

            The friendly staff helped me choose the right protein.

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