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Recombinant Rat AIMP2 Protein

Cat.No. : AIMP2-577R
Product Overview : Recombinant Rat AIMP2 full length or partial length protein was expressed.
  • Specification
  • Gene Information
  • Related Products
Source : Mammalian Cells
Species : Rat
Tag : His
Form : Liquid or lyophilized powder
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : >80%
Notes : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Storage : Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Storage Buffer : PBS buffer
Gene Name : Aimp2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 [ Rattus norvegicus ]
Official Symbol : AIMP2
Gene ID : 288480
mRNA Refseq : NM_001037348.1
Protein Refseq : NP_001032425.1
MIM :
UniProt ID : Q32PX2

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (8)

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Can AIMP2 mutations lead to human disease? 08/23/2020

Yes, mutations in AIMP2 have been associated with several human diseases. For example, a point mutation in the AIMP2 gene has been linked to Charcot-Marie-Tooth disease, a genetic disorder that affects the peripheral nerves and muscles. Additionally, a genetic variation in the promoter region of AIMP2 has been found to be associated with an increased risk of gastric cancer. Furthermore, altered AIMP2 expression levels have been observed in various other diseases, including inflammatory and autoimmune conditions, and neurodegenerative disorders.

How is AIMP2 involved in protein translation? 09/01/2019

AIMP2 is an essential component of the multi-enzyme complex called the aminoacyl-tRNA synthetase complex, which helps in the translation of genetic information from DNA into proteins. Specifically, AIMP2 functions as a subunit of the complex that connects aminoacyl-tRNA synthetases with translation factors to ensure the accurate incorporation of amino acids into proteins. AIMP2 also has additional functions in the regulation of protein synthesis, including the promotion of ribosomal biogenesis and activity.

Is AIMP2 involved in cancer development? 07/22/2018

Yes, AIMP2 has been implicated in the development and progression of various types of cancer. AIMP2 has been shown to promote cancer cell proliferation and invasion in several types of cancer, including lung, colon, and breast cancer.

Is AIMP2 involved in neurodegenerative diseases? 09/05/2017

There is evidence to suggest that AIMP2 may play a role in neurodegenerative diseases such as Alzheimer's and Parkinson's disease. AIMP2 has been found to interact with proteins involved in neural function and survival, and its expression levels have been shown to be altered in the brains of patients with these diseases.

Is AIMP2 expressed in all tissues? 11/25/2016

AIMP2 is expressed in most tissues and cell types, with particularly high levels found in the brain, liver, and muscle. AIMP2 expression levels can also be regulated by various factors such as stress, tissue injury, and inflammation.

What are some diseases associated with mutations in AIMP2? 07/28/2016

Mutations in AIMP2 are rare, but they have been implicated in Charcot-Marie-Tooth disease (CMT) type 2Z, a progressive neurological disorder that affects the peripheral nerves. Additionally, AIMP2 has been proposed as a potential therapeutic target for cancer and autoimmune disorders.

Can AIMP2 be targeted for therapeutic purposes? 09/17/2015

Yes, AIMP2 is a potential target for therapeutic interventions in cancer, inflammation, and other diseases. For example, compounds that inhibit AIMP2 have been developed and tested in preclinical studies for their potential to treat various types of cancer. In addition, targeting AIMP2 may be a potential strategy for reducing inflammation in certain disease states. However, more research is needed to determine the efficacy and safety of AIMP2-targeted therapies.

Can AIMP2 be used as a diagnostic or prognostic marker for cancer? 06/28/2015

There is some evidence to suggest that AIMP2 expression levels may be associated with cancer progression and patient outcomes, but more research is needed to determine its potential as a diagnostic or prognostic marker. In addition, AIMP2-targeted therapies are still in the early stages of development and may not be widely available.

Customer Reviews (3)

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Reviews
09/09/2022

    AIMP2 protein showcases an extraordinary level of quality, making it an optimal choice to meet my experimental demands.

    03/24/2019

      To further enhance its value, the manufacturer offers unparalleled technical support.

      02/21/2017

        The dedicated support team possesses a profound understanding of the intricacies associated with the AIMP2 protein, capable of addressing any challenges or queries I may encounter.

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