Recombinant Rat AIMP2 Protein
Cat.No. : | AIMP2-577R |
Product Overview : | Recombinant Rat AIMP2 full length or partial length protein was expressed. |
- Specification
- Gene Information
- Related Products
Source : | Mammalian Cells |
Species : | Rat |
Tag : | His |
Form : | Liquid or lyophilized powder |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | >80% |
Notes : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
Storage : | Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC. |
Storage Buffer : | PBS buffer |
Gene Name : | Aimp2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 [ Rattus norvegicus ] |
Official Symbol : | AIMP2 |
Gene ID : | 288480 |
mRNA Refseq : | NM_001037348.1 |
Protein Refseq : | NP_001032425.1 |
MIM : | |
UniProt ID : | Q32PX2 |
Products Types
◆ Recombinant Protein | ||
AIMP2-2030H | Recombinant Human AIMP2 Protein (1-320 aa), His-tagged | +Inquiry |
AIMP2-233R | Recombinant Rat AIMP2 Protein, His (Fc)-Avi-tagged | +Inquiry |
AIMP2-416M | Recombinant Mouse AIMP2 Protein, His (Fc)-Avi-tagged | +Inquiry |
AIMP2-12523Z | Recombinant Zebrafish AIMP2 | +Inquiry |
AIMP2-1458M | Recombinant Mouse AIMP2 Protein | +Inquiry |
◆ Lysates | ||
AIMP2-8951HCL | Recombinant Human AIMP2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (8)
Ask a questionYes, mutations in AIMP2 have been associated with several human diseases. For example, a point mutation in the AIMP2 gene has been linked to Charcot-Marie-Tooth disease, a genetic disorder that affects the peripheral nerves and muscles. Additionally, a genetic variation in the promoter region of AIMP2 has been found to be associated with an increased risk of gastric cancer. Furthermore, altered AIMP2 expression levels have been observed in various other diseases, including inflammatory and autoimmune conditions, and neurodegenerative disorders.
AIMP2 is an essential component of the multi-enzyme complex called the aminoacyl-tRNA synthetase complex, which helps in the translation of genetic information from DNA into proteins. Specifically, AIMP2 functions as a subunit of the complex that connects aminoacyl-tRNA synthetases with translation factors to ensure the accurate incorporation of amino acids into proteins. AIMP2 also has additional functions in the regulation of protein synthesis, including the promotion of ribosomal biogenesis and activity.
Yes, AIMP2 has been implicated in the development and progression of various types of cancer. AIMP2 has been shown to promote cancer cell proliferation and invasion in several types of cancer, including lung, colon, and breast cancer.
There is evidence to suggest that AIMP2 may play a role in neurodegenerative diseases such as Alzheimer's and Parkinson's disease. AIMP2 has been found to interact with proteins involved in neural function and survival, and its expression levels have been shown to be altered in the brains of patients with these diseases.
AIMP2 is expressed in most tissues and cell types, with particularly high levels found in the brain, liver, and muscle. AIMP2 expression levels can also be regulated by various factors such as stress, tissue injury, and inflammation.
Mutations in AIMP2 are rare, but they have been implicated in Charcot-Marie-Tooth disease (CMT) type 2Z, a progressive neurological disorder that affects the peripheral nerves. Additionally, AIMP2 has been proposed as a potential therapeutic target for cancer and autoimmune disorders.
Yes, AIMP2 is a potential target for therapeutic interventions in cancer, inflammation, and other diseases. For example, compounds that inhibit AIMP2 have been developed and tested in preclinical studies for their potential to treat various types of cancer. In addition, targeting AIMP2 may be a potential strategy for reducing inflammation in certain disease states. However, more research is needed to determine the efficacy and safety of AIMP2-targeted therapies.
There is some evidence to suggest that AIMP2 expression levels may be associated with cancer progression and patient outcomes, but more research is needed to determine its potential as a diagnostic or prognostic marker. In addition, AIMP2-targeted therapies are still in the early stages of development and may not be widely available.
Customer Reviews (3)
Write a reviewAIMP2 protein showcases an extraordinary level of quality, making it an optimal choice to meet my experimental demands.
To further enhance its value, the manufacturer offers unparalleled technical support.
The dedicated support team possesses a profound understanding of the intricacies associated with the AIMP2 protein, capable of addressing any challenges or queries I may encounter.
Ask a Question for All AIMP2 Products
Required fields are marked with *
My Review for All AIMP2 Products
Required fields are marked with *
Inquiry Basket