| Description : |
Enables several functions, including androgen binding activity; androgen receptor binding activity; and nuclear receptor activity. Involved in several processes, including cellular response to hormone stimulus; mating; and regulation of transcription, DNA-templated. Located in several cellular components, including axon; dendrite; and nucleus. Used to study hypertension; osteoporosis; prostate adenocarcinoma; prostate cancer; and prostatic hypertrophy. Biomarker of acute kidney failure and androgen insensitivity syndrome. Human ortholog(s) of this gene implicated in several diseases, including attention deficit hyperactivity disorder; conduct disorder; disorder of sexual development (multiple); reproductive organ cancer (multiple); and spinal muscular atrophy (multiple). Orthologous to human AR (androgen receptor). |
| Source : |
E. coli |
| Species : |
Rat |
| Tag : |
N-His |
| Molecular Mass : |
The protein has a calculated MW of 61 kDa. |
| AA Sequence : |
MHHHHHHLRMEVQLGLGRVYPRPPS KTYRGAFQNLFQSVREAIQNPGPRH PEAASIAPPGACLQQRQETSPRRRR RQQHPEDGSPQAHIRGTTGYLALEE EQQPSQQQSASEGHPESGCLPEPGA ATAPGKGLPQQPPAPPDQDDSAAPS TLSLLGPTFPGLSSCSADIKDILSE AGTMQLLQQQQQQQQQQQQQQQQQQ QQQQEVISEGSSSVRAREATGAPSS SKDSYLGGNSTISDSAKELCKAVSV SMGLGVEALEHLSPGEQLRGDCMYA SLLGGPPAVRPTPCAPLAECKGLSL DEGPGKGTEETAEYSSFKGGYAKGL EGESLGCSGSSEAGSSGTLEIPSSL SLYKSGAVDEAAAYQNRDYYNFPLA LSGPPHPPPPTHPHARIKLENPSDY GSAWAAAAAQCRYGDLASLHGGSVA GPSTGSPPATASSSWHTLFTAEEGQ LYGPGGGGGSSSPSDAGPVAPYGYT RPPQGLASQEGDFSASEVWYPGGVV NRVPYPSPSCVKSEMGPWMENYSGP YGDMRLDSTRDHVLPIDYYFPPQKT CLICGDEASGCHYGALTCGSCKVFF KRA |
| Purity : |
> 90% by SDS-PAGE |
| Storage : |
Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Concentration : |
0.5 mg/mL by BCA |
| Storage Buffer : |
Sterile PBS, pH 7.4 |
