Recombinant Rat Bace1 protein, His-tagged

• Cat.No.: Bace1-715R
• Product Overview: Recombinant Rat Bace1 aa. (Gly181~Tyr366 (Accession # P56819)) fused with N-terminal His tag was produced in E. coli cells.

Specification

• Description: Catalyzes the cleavage of the beta site of amyloid precursor protein; may play a role in generation of amyloid beta peptide.
• Source: E. coli
• Species: Rat
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: 24kDa as determined by SDS-PAGE reducing conditions
• Protein length: Gly181~Tyr366 (Accession # P56819)
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 5.7.
• Applications: SDS-PAGE; WB; ELISA; IP
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: Bace1 beta-secretase 1 [ Rattus norvegicus (Norway rat) ]
• Official Symbol: Bace1
• Synonyms: Bace1; beta-secretase 1; Bace; beta-secretase 1; ASP2; asp 2; aspartyl protease 2; beta-site APP cleaving enzyme 1; beta-site amyloid precursor protein cleaving enzyme 1; memapsin-2; membrane-associated aspartic protease 2
• Gene ID: 29392
• mRNA Refseq: NM_019204.2
• Protein Refseq: NP_062077.1
• UniProt ID: P56819