Recombinant Rat Casp4 Protein, His-tagged
Cat.No. : | Casp4-626R |
Product Overview : | Recombinant Rat Casp4 Protein (Met1-Asn373) with His tag was expressed in E. coli. |
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- Gene Information
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Description : | Enables scaffold protein binding activity. Predicted to be involved in several processes, including cellular response to amyloid-beta; positive regulation of tumor necrosis factor-mediated signaling pathway; and protein autoprocessing. Predicted to act upstream of or within ectopic germ cell programmed cell death; positive regulation of interleukin-1 beta production; and pyroptosis. Located in neuron projection and neuronal cell body. Part of protein-containing complex. Orthologous to human CASP4 (caspase 4). |
Source : | E. coli |
Species : | Rat |
Tag : | N-His |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 46.4 kDa; Accurate Molecular Mass: 46 kDa |
Protein length : | Met1-Asn373 |
Purity : | > 90% |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Storage Buffer : | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
Reconstitution : | Reconstitute in PBS or others. |
Gene Name : | Casp4 caspase 4, apoptosis-related cysteine peptidase [ Rattus norvegicus (Norway rat) ] |
Official Symbol : | Casp4 |
Synonyms : | CASP4; caspase 4, apoptosis-related cysteine peptidase; caspase 4; caspase 11; Casp11; MGC124949; |
Gene ID : | 114555 |
mRNA Refseq : | NM_053736 |
Protein Refseq : | NP_446188 |
UniProt ID : | E9PSM0 |
Products Types
◆ Recombinant Protein | ||
CASP4-0424H | Recombinant Human CASP4 Protein, GST-Tagged | +Inquiry |
CASP4-01H | Active Recombinant Human CASP4 Protein | +Inquiry |
CASP4-2594H | Recombinant Human CASP4 Protein, His (Fc)-Avi-tagged | +Inquiry |
CASP4-1244M | Recombinant Mouse CASP4 Protein, His (Fc)-Avi-tagged | +Inquiry |
CASP4-462R | Recombinant Rhesus Macaque CASP4 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CASP4-7837HCL | Recombinant Human CASP4 293 Cell Lysate | +Inquiry |
CASP4-7836HCL | Recombinant Human CASP4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionCASP4 protein is involved in the recognition of bacterial lipopolysaccharide (LPS) and the initiation of the inflammatory response, which can contribute to the development of sepsis.
CASP4 protein interacts with other caspases and inflammatory mediators, contributing to the amplification of the inflammatory response.
CASP4 protein plays a role in the activation of inflammatory pathways and the production of inflammatory cytokines in response to bacterial infection.
Several pharmaceutical companies are researching potential inhibitors of CASP4 protein as a strategy for treating inflammatory conditions.
Elevated levels of CASP4 protein in the blood may indicate the presence of inflammation or infection, and could be used as a diagnostic marker for such conditions.
Customer Reviews (3)
Write a reviewBy relying on the CASP4 protein and the manufacturer's exceptional technical support, researchers can confidently pursue their experimental goals while knowing they have access to reliable resources and expert guidance.
Its reliable and accurate performance ensures dependable results, contributing to the advancement of scientific knowledge in various disciplines.
In addition to their expertise, the manufacturer's technical support team can assist in troubleshooting and optimizing the handling and application of the CASP4 protein.
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