Recombinant Rat Ccn2 Protein, Full Length
Cat.No. : | CTGF-14RFL |
Product Overview : | Recombinant Rat Ccn2 Protein (Full Length) without tag was expressed in Human embryonic kidney cell. |
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Description : | Enables fibronectin binding activity and growth factor activity. Involved in several processes, including positive regulation of G0 to G1 transition; positive regulation of collagen biosynthetic process; and positive regulation of macromolecule metabolic process. Located in several cellular components, including cell cortex; cis-Golgi network; and perinuclear region of cytoplasm. Used to study endomyocardial fibrosis. Biomarker of several diseases, including artery disease (multiple); lung disease (multiple); membranoproliferative glomerulonephritis; primary biliary cholangitis; and restrictive cardiomyopathy (multiple). Orthologous to human CCN2 (cellular communication network factor 2). |
Source : | HEK293 |
Species : | Rat |
Protein length : | Full length |
Bio-activity : | Measured by its ability to mediate Balb/3T3 mouse embryonic fibroblast cell adhesion. The ED50 for this effect is 1-5 μg/mL |
Molecular Mass : | Predicted Molecular Mass: 35 kDa SDS-PAGE: 35-41 kDa, reducing conditions |
Endotoxin : | < 0.10 EU/μg of the protein by the LAL method. |
Purity : | > 85%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie Blue Staining. |
N-terminal Sequence Analysis : | No results obtained. Gln25 inferred from enzymatic pyroglutamate treatment revealing Asp26 |
Storage : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution in PBS and NaCl. |
Shipping : | At ambient temperature |
Reconstitution : | Reconstitute at 500 μg/mL in water. |
References : | 1. Hall-Glenn, F. and K.M. Lyons (2011) Cell. Mol. Life Sci. 68:3209. 2. Xu, J. et al. (2000) J. Cell. Biochem. 77:103. 3. Gao, R. and D.R. Brigstock (2004) J. Biol. Chem. 279:8848. |
Gene Name : | Ccn2 cellular communication network factor 2 [ Rattus norvegicus (Norway rat) ] |
Official Symbol : | Ccn2 |
Synonyms : | Ccn2; cellular communication network factor 2; Ctgf; CTGRP; CCN family member 2; connective tissue growth factor; connective tissue growth-related protein |
Gene ID : | 64032 |
mRNA Refseq : | NM_022266 |
Protein Refseq : | NP_071602 |
UniProt ID : | Q9R1E9 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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