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Recombinant Rat Cd200 Protein, His&GST-tagged

Cat.No. : Cd200-660R
Product Overview : Recombinant Rat Cd200 Protein (Ala47-Ser271) with His&GST tag was expressed in E. coli.
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Description : Enables protein binding activity involved in heterotypic cell-cell adhesion. Involved in several processes, including negative regulation of interleukin-6 production; negative regulation of leukocyte migration; and negative regulation of neuroinflammatory response. Located in cell surface; neuron projection; and neuronal cell body. Orthologous to human CD200 (CD200 molecule).
Source : E. coli
Species : Rat
Tag : His&GST
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 55.1 kDa; Accurate Molecular Mass: 43 kDa
Protein length : Ala47-Ser271
Purity : > 90%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Storage Buffer : PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Reconstitution : Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Gene Name : Cd200 Cd200 molecule [ Rattus norvegicus (Norway rat) ]
Official Symbol : Cd200
Synonyms : CD200; Cd200 molecule; OX-2 membrane glycoprotein; Cd200 antigen; MRC OX-2 antigen; antigen identified by monoclonal MRC OX-2; Cell surface protein (thymocyte antigen identified by monoclonal MRC-OX2; cell surface protein (thymocyte antigen identified by monoclonal MRC-OX2); Mox2; Cspmo2; MRCOX2; MGC108657;
Gene ID : 24560
mRNA Refseq : NM_031518
Protein Refseq : NP_113706
UniProt ID : A0A5D0

Not For Human Consumption!

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Customer Reviews (3)

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Reviews
08/01/2022

    Swift protein sequencing, helps identify unknown proteins.

    05/04/2022

      Great protein crystallization services, key for structural biology.

      05/02/2019

        Invaluable protein-protein interaction assays, integral for research.

        Q&As (7)

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        How does CD200 contribute to the regulation of bone marrow and hematopoietic stem cell niches? 10/04/2022

        CD200 regulates bone marrow and hematopoietic environments, supporting stem cell maintenance and differentiation.

        How does CD200 influence tumor immune evasion and the tumor microenvironment in cancer? 07/10/2021

        CD200 contributes to immune evasion in cancers, affecting tumor progression and response to immunotherapy.

        What role does CD200 play in the suppression of inflammatory responses in autoimmune diseases? 04/06/2021

        CD200 plays a role in suppressing inflammatory responses, which is crucial in autoimmune disease management.

        What are the effects of CD200 dysregulation on tissue graft rejection and transplant tolerance? 02/09/2019

        Dysregulation of CD200 affects tissue graft rejection, influencing transplant tolerance and success.

        How do alterations in CD200 expression impact the aging process and age-related immune changes? 09/17/2018

        Changes in CD200 expression impact the aging immune system, affecting age-related immune regulation and function.

        What is the impact of CD200 expression on neuroinflammatory processes and neurodegenerative diseases? 03/20/2018

        CD200 expression influences neuroinflammatory processes, potentially impacting neurodegenerative diseases.

        How does CD200 interact with its receptor CD200R, and what are the implications for immune regulation? 03/18/2018

        CD200 interacts with CD200R to modulate immune responses, promoting immune tolerance and reducing inflammation.

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