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Recombinant Rat Cd46 protein, His & GST-tagged

Cat.No. : Cd46-6756R
Product Overview : Recombinant Rat Cd46 aa. (Met136~Val341) fused with N-terminal His & GST tag was produced in E. coli cells.
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Source : E. coli
Species : Rat
Tag : His&GST
Form : Freeze-dried powder
Molecular Mass : 53kDa as determined by SDS-PAGE reducing conditions.
Protein length : Met136~Val341
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >92%
Characteristic : The isoelectric point is 7.2.
Applications : SDS-PAGE; WB; ELISA; IP; CoIP; Purification; Amine Reactive Labeling.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for two years.
Concentration : 200ug/mL
Storage buffer : 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% Trehalose and Proclin300.
Reconstitution : Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0mg/mL. Do not vortex.
Gene Name : Cd46 CD46 molecule [ Rattus norvegicus (Norway rat) ]
Official Symbol : Cd46
Synonyms : Mcp; membrane cofactor protein; CD46 antigen, complement regulatory protein; CD46 molecule, complement regulatory protein
Gene ID : 29333
mRNA Refseq : NM_019190.1
Protein Refseq : NP_062063.1
UniProt ID : Q9Z0M4

Not For Human Consumption!

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Customer Reviews (3)

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Reviews
10/19/2022

    The CD46 protein offers numerous advantages in trials and research studies, making it an excellent choice for scientists in need of reliable and high-quality experimental materials.

    08/09/2019

      With the CD46 protein and its accompanying technical assistance, I am confident that I can achieve successful outcomes for my research endeavors.

      03/05/2019

        Its unique properties make CD46 an invaluable tool for investigating cellular signaling pathways, protein-protein interactions, and membrane dynamics.

        Q&As (5)

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        How does CD46 protein interact with other immune system components? 08/20/2021

        CD46 protein interacts with complement regulatory proteins and immune cells to regulate immune responses and maintain homeostasis.

        What are the potential side effects of targeting CD46 protein for therapy? 01/05/2020

        Potential side effects of targeting CD46 protein for therapy may include disturbances in immune regulation and increased susceptibility to infections.

        How does the CD46 protein contribute to immune regulation? 08/11/2018

        CD46 protein regulates the activation of complement system and modulates T cell responses, contributing to immune regulation.

        Can mutations in the CD46 gene lead to genetic disorders? 09/22/2017

        Mutations in the CD46 gene have been associated with genetic disorders such as atypical hemolytic uremic syndrome (aHUS) and other complement-related disorders.

        Is CD46 protein involved in cancer progression or treatment resistance? 08/07/2016

        CD46 protein has been implicated in cancer progression and treatment resistance, particularly in certain types of leukemia and solid tumors.

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