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Recombinant Rat Endog Protein, His/GST-tagged

Cat.No. : Endog-697R
Product Overview : Recombinant Rat Endog(Met1~Lys294) fused with His tag at N-terminal was expressed in E. coli.
  • Specification
  • Gene Information
  • Related Products
Source : E. coli
Species : Rat
Tag : His/GST
Form : PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Molecular Mass : 62.3kDa
Protein length : Met1~Lys294
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : > 95%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution : Reconstitute in PBS or others
Gene Name : Endog endonuclease G [ Rattus norvegicus ]
Official Symbol : Endog
Synonyms : ENDOG; endonuclease G; endonuclease G, mitochondrial;
Gene ID : 362100
mRNA Refseq : NM_001034938
Protein Refseq : NP_001030110

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the structure ENDOG? 09/17/2022

The structure of ENDOG includes multiple functional domains, including a hydrophobic transmembrane domain at the N-terminus, an uncoupling domain at the intermediate, and a proton pump domain at the C-terminus.

How is ENDOG involved in the uncoupling of the inner mitochondrial membrane? 01/25/2022

It catalyzes the electron transfer of NADH+H⁺ to the outside mitochondria via the uncoupling domain, while converting the proton electrochemical gradient of the inner mitochondrial membrane into heat energy.

How it affects energy metabolism and nutrient metabolism ENDOG? 11/14/2021

ENDOG regulates mitochondrial energy metabolism and nutrient metabolism processes through uncoupling and proton pump action. For example, it can transfer electrons of NADH+H⁺ to the outside of mitochondria while converting the proton electrochemical gradient of the inner mitochondrial membrane into heat energy.

Is it related to other ENDOG proteins? 09/03/2021

ENDOG HAS A VARIETY OF ASSOCIATIONS WITH OTHER PROTEINS. For example, it may interact with other proteins on the inner mitochondrial membrane to co-participate in mitochondrial function, and it may also interact with proteins in signal transduction pathways to participate in cell signaling.

What are the differences in the expression levels of ENDOG in different tissues and cells? 05/31/2021

There are differences in the expression levels of ENDOG in different tissues and cells. For example, it is expressed higher in muscle tissue and lower in brain tissue. This difference may be related to the energy requirements and metabolic characteristics of different tissues and cells.

What conditions might be indicated by abnormal ENDOG levels? 04/29/2021

Abnormal ENDOG levels may indicate a variety of diseases, especially tumors, neurodegenerative diseases, etc. For example, in tumors such as lung, breast, and colon cancer, expression levels of ENDOG may be abnormally elevated.

Customer Reviews (3)

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Reviews
04/24/2022

    This protein synthesis process is efficient and reliable, reducing experimental time and cost.

    12/27/2021

      ENDOG is easy to purify and manipulate, which improves the experimental efficiency.

      11/22/2021

        The sensitivity and accuracy of the experiment were significantly improved by using this protein.

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