Recombinant Rat Fgf7 protein, His/S-tagged

Cat.No.: Fgf7-191R
Product Overview: Recombinant Rat Fgf7 fused with His/S tag was expressed in E. coli.
Description: KGF is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis.
Source: E. coli
Species: Rat
Tag : His/S
Form: Lyophilized from sterile PBS, pH 7.4
Purity: > 95 % as determined by SDS-PAGE
Storage: Store at -70 centigrade. Avoid repeated freeze/thaw cycles.
Gene Name: Fgf7 fibroblast growth factor 7 [ Rattus norvegicus ]
Official Symbol: Fgf7
Synonyms: FGF7; fibroblast growth factor 7; FGF-7; HBGF-7; keratinocyte growth factor; heparin-binding growth factor 7; Kgf;
Gene ID: 29348
mRNA Refseq: NM_022182
Protein Refseq: NP_071518
UniProt ID: Q02195
Chromosome Location: 3q36
Pathway: Downstream signaling of activated FGFR, organism-specific biosystem; FGFR ligand binding and activation, organism-specific biosystem; FGFR2 ligand binding and activation, organism-specific biosystem; FGFR2b ligand binding and activation, organism-specific biosystem; FRS2-mediated cascade, organism-specific biosystem; IRS-mediated signalling, organism-specific biosystem; IRS-related events, organism-specific biosystem;
Function: chemoattractant activity; chemoattractant activity; growth factor activity; heparin binding; type 2 fibroblast growth factor receptor binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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