Active Recombinant Rat FGFR4 Protein, Fc-tagged
Cat.No. : | FGFR4-1076R |
Product Overview : | Recombinant rat FGFR4 (Q498D6) extracellular domain (Met 1-Asp 367) was fused with the Fc region of human IgG1 at the C-terminus. |
- Specification
- Gene Information
- Related Products
Source : | HEK293 |
Species : | Rat |
Tag : | Fc |
Predicted N Terminal : | Phe 17 |
Form : | Lyophilized from sterile PBS, pH 7.4, 5%~8% trehalose and mannitol. |
Bio-activity : | 1. Measured by its binding ability in a functional ELISA. 2. Immobilized human FGF18 at 10 μg/mL (100 μl/well) can bind Rat FGFR4, The EC50 of Rat FGFR4 is 1.17 μg/mL. 3. Immobilized mouse FGF18 at 10 μg/mL (100 μl/well) can bind Rat FGFR4, The EC50 of Ra |
Molecular Mass : | The recombinant rat FGFR4/Fc is a disulfide-linked homodimer. The reduced monomer comprises 592 amino acids and predicts a molecular mass of 66 kDa. The apparent molecular mass of the rat FGFR4/Fc monomer is approximately 110 kDa in SDS-PAGE under reducing conditions due to glycosylation. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | >90 % as determined by SDS-PAGE. |
Stability : | Samples are stable for up to twelve months from date of receipt at -70ºC. |
Storage : | Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | Fgfr4 fibroblast growth factor receptor 4 [ Rattus norvegicus ] |
Official Symbol : | FGFR4 |
Synonyms : | FGFR4; fibroblast growth factor receptor 4; FGFR-4; MGC116290; |
Gene ID : | 25114 |
mRNA Refseq : | NM_001109904 |
Protein Refseq : | NP_001103374 |
MIM : | |
UniProt ID : | |
Pathway : | Downstream signaling of activated FGFR, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; FGFR ligand binding and activation, organism-specific biosystem; FGFR4 ligand binding and activation, organism |
Function : | ATP binding; fibroblast growth factor 1 binding; fibroblast growth factor 1 binding; fibroblast growth factor 2 binding; fibroblast growth factor 2 binding; fibroblast growth factor binding; fibroblast growth factor-activated receptor activity; fibroblast |
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◆ Lysates | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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