"FGFR4" Related Products

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Recombinant Rat FGFR4 Protein, Fc-tagged

Cat.No.: FGFR4-1076R
Product Overview: Recombinant rat FGFR4 (Q498D6) extracellular domain (Met 1-Asp 367) was fused with the Fc region of human IgG1 at the C-terminus.
Source: HEK293
Species: Rat
Tag: Fc
Predicted N Terminal: Phe 17
Form: Lyophilized from sterile PBS, pH 7.4, 5%~8% trehalose and mannitol.
Bio-activity: 1. Measured by its binding ability in a functional ELISA. 2. Immobilized human FGF18 at 10 μg/mL (100 μl/well) can bind Rat FGFR4, The EC50 of Rat FGFR4 is 1.17 μg/mL. 3. Immobilized mouse FGF18 at 10 μg/mL (100 μl/well) can bind Rat FGFR4, The EC50 of Ra
Molecular Mass: The recombinant rat FGFR4/Fc is a disulfide-linked homodimer. The reduced monomer comprises 592 amino acids and predicts a molecular mass of 66 kDa. The apparent molecular mass of the rat FGFR4/Fc monomer is approximately 110 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Purity: >90 % as determined by SDS-PAGE.
Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Gene Name: Fgfr4 fibroblast growth factor receptor 4 [ Rattus norvegicus ]
Official Symbol: FGFR4
Synonyms: FGFR4; fibroblast growth factor receptor 4; FGFR-4; MGC116290;
Gene ID: 25114
mRNA Refseq: NM_001109904
Protein Refseq: NP_001103374
MIM:
UniProt ID:
Pathway: Downstream signaling of activated FGFR, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; FGFR ligand binding and activation, organism-specific biosystem; FGFR4 ligand binding and activation, organism
Function: ATP binding; fibroblast growth factor 1 binding; fibroblast growth factor 1 binding; fibroblast growth factor 2 binding; fibroblast growth factor 2 binding; fibroblast growth factor binding; fibroblast growth factor-activated receptor activity; fibroblast

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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