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Recombinant Rat Il6st, Fc-His tagged

Cat.No. : Il6st-4091R
Product Overview : Recombinant Rat Il6st (NP_001008725.2) extracellular domain (Met 4-Glu 618), fused with the C-terminal polyhistidine-tagged Fc region of mouse IgG1, was produced in Human Cell.
Availability February 17, 2025
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Source : Human Cells
Species : Rat
Tag : His&Fc
Form : Lyophilized from sterile PBS, pH 7.4
Molecular Mass : The recombinant rat IL6ST/Fc is a disulfide-linked homodimer. The reduced monomer comprises 839 amino acids and predicts a molecular mass of 94.3 kDa. The apparent molecular mass of the rat IL6ST/Fc monomer is approximately 130 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Endotoxin : < 1.0 eu per μg of the protein as determined by the LAL method.
Stability : Samples are stable for up to twelve months from date of receipt at -70oC.
Storage : Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Protein length : Met4-Glu618
Gene Name : Il6st interleukin 6 signal transducer [ Rattus norvegicus ]
Official Symbol : Il6st
Gene ID : 25205
mRNA Refseq : NM_001008725
Protein Refseq : NP_001008725

Not For Human Consumption!

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Customer Reviews (3)

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Reviews
02/28/2022

    IL6ST proteins can be functionally enhanced or altered by protein modification techniques.

    08/04/2020

      As an immunotherapy drug, it has good effect and high safety.

      09/06/2019

        Has a good inhibitory effect on cell proliferation and survival.

        Q&As (6)

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        How to detect IL6ST activity? 04/26/2022

        The activity of IL6ST is usually detected by cell differentiation and proliferation assay.

        In what diseases does IL6ST have applications? 04/20/2021

        IL6ST may be used in the future to treat pulmonary fibrosis, chronic pulmonary obstruction, rheumatoid arthritis, and other chronic kidney diseases.

        Are there any effects of IL6ST on cell differentiation? 04/15/2021

        IL6ST is involved in various inflammatory responses and cell differentiation processes.

        What are the physical and chemical properties of IL6ST? 02/03/2021

        The physical and chemical properties of IL6ST include molecular weight, voltammetry potential, structure and stability.

        Why research IL6ST? 02/09/2019

        The study of IL6ST helps us to better understand the disease mechanism involved in IL6ST, and provides new ideas and means for disease treatment.

        What is the preparation method of IL6ST? 01/27/2019

        The IL6ST is usually prepared by transforming E. coli into an expression vector and making it express the IL6ST protein.

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