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Recombinant Rat Interleukin 18

Cat.No. : Il18-522R
Product Overview : Recombinant rat IL-18 is a single,non-glycosylated polypeptide containing 158 amino acids and having amolecular weight of 18.3 kDa.
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  • Gene Information
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Cat. No. : Il18-522R
Description : Interleukin-18also known as IL18 is a protein which in humans is encoded by the IL18 gene.The protein encoded by this gene is a proinflammatory cytokine.
Biological Activity : The Rat IL-18 isfully biologically active when compared to standard. The ED50 asdetermined by the dose-dependent stimulation of IFN- gamma by murine lymphnode cells, stimulated with sub optimal dose of ConA (0.75 µg/ml) is 12ng/ml.
Molecular Weight : 18.3 kDa
Source : E.coli
Species : Rat
Form : Lyophilized (from 1mg/ml in 0.4X PBS)
Appearance : Lyophilized protein
Endotoxin Level : <0.1 ng/µg
Reconstitution : Reconstitute inwater to a concentration of 0.1-1.0 µg/µl. Gentle pipetting to mix it well.The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or -20°C for future use.
Purity : >95% by SDS-PAGEand HPLC analysis
Storage : Thelyophilized IL-18 is best-stored desiccated below 0°C. Reconstituted IL-18飥?should be stored at working aliquots at -20°C.
Pathways : African trypanosomiasis;Cytokine-cytokine receptor interaction; Cytosolic DNA-sensing pathway;Hypertrophy Model; Influenza A; Legionellosis; Malaria; NOD-like receptorsignaling pathway; Rheumatoid arthritis; Salmonella infection; Tuberculosis
Gene Name : Il18 interleukin 18 [ Rattus norvegicus]
Official Symbol : Il18
Synonyms : Il18; interleukin 18; IL-18;IGIF; interleukin-18; IL-1 gamma; interleukin-1 gamma; IFN-gamma-inducingfactor; interferon gamma-inducing factor; interleukin 18(interferon-gamma-inducing factor); MGC12320; IL1F4; iboctadekin; IL-1g;Interferon gamma-inducing factor; Iboctadekin; Interleukin-1 gamma
Gene ID : 29197
mRNA Refseq : NM_019165
Protein Refseq : NP_062038
UniProt ID : P97636
Chromosome Location : 8q23
Function : cytokine activity; interleukin-18receptor binding; protein binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.



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