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Recombinant Rat NOX4 Protein (210-424 aa), His-B2M-tagged

Cat.No. : NOX4-2200R
Product Overview : Recombinant Rat NOX4 Protein (210-424 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-B2M tag at the N-terminal. Research Area: Cardiovascular. Protein Description: Partial.
  • Specification
  • Gene Information
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Description : Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB.
Source : E. coli
Species : Rat
Tag : His-B2M
Form : Tris-based buffer,50% glycerol
Molecular Mass : 38.6 kDa
Protein length : 210-424 aa
AA Sequence : GGLLKYQTNLDTHPPGCISLNRTPS QNMSIADYVSEHFHGSLPGGFSKLE DHYQKTLVKICLEEPKFQAHFPQTW IWISGPLCLYCAERLYRCIRSNKPV TIISVINHPSDVMELRMIKENFKAR PGQYIILHCPSVSALENHPFTLTMC PTETKATFGVHFKVVGDWTERFRDL LLPPSSQDSEILPFIQSRNYPKLYI DGPFGSPFEESLNYE
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA will be sent along with the products. Please refer to it for detailed information.
Gene Name : Nox4 NADPH oxidase 4 [ Rattus norvegicus ]
Official Symbol : NOX4
Synonyms : NOX4; NADPH oxidase 4; kox-1; kidney oxidase-1; kidney superoxide-producing NADPH oxidase;
Gene ID : 85431
mRNA Refseq : NM_053524
Protein Refseq : NP_445976
UniProt ID : Q924V1

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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