Recombinant Rat NPR3 Protein (41-477 aa), His-SUMO-tagged

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Recombinant Rat NPR3 Protein (41-477 aa), His-SUMO-tagged

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Cat.No. : NPR3-692R
Product Overview : Recombinant Rat NPR3 Protein (41-477 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Protein Description: Partial.
Description : Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity.
Source : E. coli
Species : Rat
Tag : His-SUMO
Form : Tris-based buffer, 50% glycerol
Molecular Mass : 64.9 kDa
Protein length : 41-477 aa
AA Sequence : EALAAQKIEV LVLLPRDDSY LFSLARVRPA IEYALRSVEG NGTGRKLLPP GTRFQVAYED SDCGNRALFS LVDRVAAARG AKPDLILGPV CEYAAAPVAR LASHWDLPML SAGALAAGFQ HKDTEYSHLT RVAPAYAKMG EMMLALFRHH HWSRAALLYS DDKLERNCYF TLEGVHEVFQ EEGLHTSAYN FDETKDLDLD DIVRYIQGSE RVVIMCASGD TIRRIMLAVH RHGMTSGDYA FFNIELFNSS SYGDGSWKRG DKHDFEAKQA YSSLQTVTLL RTAKPEFEKF SMEVKSSVEK QGLNEEDYVN MFVEGFHDAI LLYVLALHEV LRAGYSKKDG GKIIQQTWNR TFEGIAGQVS IDANGDRYGD FSVVAMTDTE AGTQEVIGDY FGKEGRFKMR SNVKYPWGSL KLRIDETRIV EHTNSSPCKS CGLEESA
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with concentration instruction is sent along with the products.
Figure :

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Gene Name : Npr3 natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) [ Rattus norvegicus ]
Official Symbol : NPR3
Synonyms : NPR3; ANP-C; ANPRC; NPR-C; ANPR-C; NPRC; ANP-CR;
Gene ID : 25339
mRNA Refseq : NM_012868
Protein Refseq : NP_037000
UniProt ID : P41740

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