| Description : |
Predicted to be involved in negative regulation of immune response and positive regulation of T cell apoptotic process. Predicted to act upstream of or within negative regulation of apoptotic process; negative regulation of tolerance induction; and positive regulation of apoptotic process. Located in plasma membrane. Biomarker of anti-basement membrane glomerulonephritis; periodontitis; and pre-eclampsia. Human ortholog(s) of this gene implicated in autoimmune disease (multiple); hepatitis B; hepatitis C; hepatocellular carcinoma; and lupus nephritis. Orthologous to human PDCD1 (programmed cell death 1). |
| Source : |
HEK293 |
| Species : |
Rat |
| Form : |
Lyophilized |
| Molecular Mass : |
18.1 kDa |
| Protein Length : |
287 |
| AA Sequence : |
MWVQQVPWSFTWAVLQLSWQSGWLL EVLNKPWRPLTFSPTWLTVSEGANA TFTCSFSNWSEDLKLNWYRLSPSNQ TEKQAAFCNGYSQPVRDARFQIVQL PNGHDFHMNILDARRNDSGIYLCGA ISLPPKAQIKESPGAELVVTERILE TPTRYPRPSPKPEGQFQGLVIVIMS VLVGIPVLLLLAWALAAFCSTGMSE AREAGRKEDPPKEAHAAAPVPSVAY EELDFQGREKTPEPAPCVHTEYATI VFTEGLDASAIGRRGSADGPQGPRP PRHEDGHCSWPL |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
