"Pde7a" Related Products


Recombinant Rat Pde7a protein, GST-tagged

Cat.No.: Pde7a-1543R
Product Overview: Recombinant Rat Pde7a(147–482 aa) fused with GST tag at N-terminal was expressed in Insect cells.
Source: Insect cells
Species: Rat
Tag : GST
Form: 45 mM Tris-HCl, pH 8.0, 124 mM NaCl, 2.4 mM KCl, 18 mM glutathione, 10% glycerol, and 3 mM DTT.
Bio-activity: ≥354 pmol/min/µg.
Molecular Mass: 65 kDa
Unit Definition: One unit is defined as the amount of enzyme that will convert 1 pmole of 3', 5'-cAMP to 5'-AMP per minute at 37 centigrade.
Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Storage: >6 months at -80 centigrade. Avoid freeze/thaw cycles.
Concentration: 0.34 mg/ml
Gene Name: Pde7a phosphodiesterase 7A [ Rattus norvegicus ]
Official Symbol: Pde7a
Synonyms: PDE7A; phosphodiesterase 7A; high affinity cAMP-specific 3,5-cyclic phosphodiesterase 7A; rolipram-insensitive phosphodiesterase type 7; PDE7-1;
Gene ID: 81744
mRNA Refseq: NM_031080
Protein Refseq: NP_112342
Chromosome Location: 2q24
Pathway: G Protein Signaling Pathways, organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; Morphine addiction, organism-specific biosystem; Morphine addiction, conserved biosystem; Purine metabolism, organism-specific biosystem; Purine metabolism, conserved biosystem;
Function: 3,5-cyclic-AMP phosphodiesterase activity; 3,5-cyclic-AMP phosphodiesterase activity; 3,5-cyclic-AMP phosphodiesterase activity; cyclic-nucleotide phosphodiesterase activity; hydrolase activity; metal ion binding; phosphoric diester hydrolase activity;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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