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Recombinant Rat PLN Protein

Cat.No. : PLN-4529R
Product Overview : Recombinant Rat PLN full length or partial length protein was expressed.
  • Specification
  • Gene Information
  • Related Products
Source : Mammalian Cells
Species : Rat
Tag : His
Form : Liquid or lyophilized powder
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : >80%
Notes : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Storage : Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Storage Buffer : PBS buffer
Gene Name : Pln phospholamban [ Rattus norvegicus ]
Official Symbol : PLN
Gene ID : 64672
mRNA Refseq : NM_022707.2
Protein Refseq : NP_073198.1
MIM :
UniProt ID : P61016

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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What is the role of PLN in the regulation of cardiac contractility? 05/11/2022

PLN regulates cardiac contractility by fine-tuning calcium cycling, influencing the force of myocardial contractions.

How does PLN contribute to the pathophysiology of heart failure? 07/03/2021

Dysregulation of PLN in heart failure results in impaired calcium handling, contributing to contractile dysfunction and the progression of heart failure.

Can you explain the structural features of PLN and its interaction with SERCA? 11/08/2020

PLN has a transmembrane domain and interacts with SERCA through its cytoplasmic domain, forming a complex that modulates calcium transport.

How does phosphorylation regulate the activity of PLN? 04/16/2019

Phosphorylation of PLN at specific sites, particularly by protein kinase A (PKA), relieves its inhibitory effect on SERCA, enhancing calcium reuptake into the sarcoplasmic reticulum.

What is the molecular function of PLN in the context of muscle contraction? 08/27/2018

PLN regulates muscle contraction by inhibiting the activity of the sarcoplasmic reticulum calcium pump (SERCA), modulating intracellular calcium levels.

Customer Reviews (3)

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Reviews
03/16/2022

    Customer service provided valuable insights into the applications of this product, helping us make an informed decision.

    03/02/2019

      The team promptly addressed my inquiries and provided valuable assistance in selecting the right recombined protein for our research.

      06/23/2018

        Lightning-fast delivery!

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