Recombinant Rat RPS6 Protein Pre-coupled Magnetic Beads

• Cat.No.: RPS6-4830R-B
• Product Overview: The Recombnant protein was conjugated to magnetic beads. This ready-to-use, pre-coupled magnetic beads are in uniform particle size and narrow size distribution with large surface area, which is conducive to convenient and fast capture target molecules with high specificity and achieve magnetic separation. This product can be equipped with automation equipment for high-throughput operations.

Specification

• Source: HEK293
• Species: Rat
• Form: Solution
• Particle size: ~2 μm
• Beads Surface: Hydrophilic
• Capacity: > 200 pmol rabbit IgG/ mg beads
• Applications: Immunoassay, In vitro diagnostics, cell sorting, Immunoprecipitation/Co-precipitation, Protein/antibody separation and purification.
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions.
• Storage: 2-8℃. Do not to freeze thaw the Beads
• Concentration: 10mg beads/mL
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Rps6 ribosomal protein S6 [ Rattus norvegicus ]
• Official Symbol: RPS6
• Gene ID: 29304
• mRNA Refseq: NM_017160.1
• Protein Refseq: NP_058856.1
• UniProt ID: P62755

Reviews

11/11/2022

The reproducibility is good, and the results of multiple experiments are consistent.

04/16/2022

The expression level is high, the stability is good, and it is suitable for experiments with high precision requirements.

06/14/2021

They have a wide range of products and can always find the recombinant protein we need.

Q&As

How about the localization and role of RPS6 in cells?

RPS6 is mainly located on ribosomes in the cytoplasm and is involved in the regulation of protein translation. It is able to bind to and respond to the 5' cap structure on mRNA, regulating the initiation and efficiency of translation. In addition, RPS6 is also involved in the regulation of cell signal transduction and gene expression.

What are the limitations of the studies on RPS6?

There are still some limitations in the current research on RPS6, such as the lack of in-depth research on its specific mechanism of action and function, and the incomplete understanding of its relationship with diseases. In addition, since RPS6 is an important component in the cytoplasm, its regulation may also have some side effects.

What diseases may be caused by mutations or variants in RPS6?

Mutations or variants in RPS6 may lead to some genetic diseases such as Charcot-Marie-Tooth disease (CMT) and peripheral neuropathy. These disorders usually manifest as damage and dysfunction of peripheral nerves.

Are there novel RPS6 mechanisms or functions in recent studies?

Recent studies have found that RPS6 is also involved in processes such as autophagy and apoptosis. These processes have an important impact on cell survival and death, and also provide new ideas for the treatment of some diseases related to RPS6.

Is there a relationship between RPS6 expression levels and disease?

Some studies have shown that RPS6 expression levels are associated with a variety of diseases. For example, in some cancers, RPS6 expression levels are upregulated, which promotes the growth and proliferation of tumor cells. In neurodegenerative diseases, RPS6 expression levels may be down-regulated, leading to cell death.

How is RPS6 expression regulated?

The expression of RPS6 is regulated by a variety of factors, including upstream transcription factors, signal transduction pathways, and environmental factors. For example, the mTORC1 signaling pathway can regulate the expression level of RPS6, while nutrients, hormones, and growth factors can also affect the expression of RPS6.