Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Rat SORT1 Protein (610-754 aa), His-tagged

Cat.No. : SORT1-1527R
Product Overview : Recombinant Rat SORT1 Protein (610-754 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Protein Description: Partial.
  • Specification
  • Gene Information
  • Related Products
Description : Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the Extracellular domain matrix during osteogenic differentiation by scavenging Extracellular domain LPL. Probably required in adipocytes for the formation of specialized storage vesicles containing the glucose transporter SLC2A4/GLUT4 (GLUT4 storage vesicles, or GSVs). These vesicles provide a stable pool of SLC2A4 and confer increased responsiveness to insulin. May also mediate transport from the endoplasmic reticulum to the Golgi.
Source : Yeast
Species : Rat
Tag : His
Form : Tris-based buffer,50% glycerol
Molecular Mass : 18.5 kDa
Protein length : 610-754 aa
AA Sequence : CEENDYTTWLAHSTDPGDYKDGCIL GYKEQFLRLRKSSVCQNGRDYVVAK QPSICPCSLEDFLCDFGYFRPENAS ECVEQPELKGHELEFCLYGKEEHLT TNGYRKIPGDRCQGGMNPAREVKDL KKKCTSNFLNPKKQNSKSSS
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with reconstitution instruction is sent along with the products.
Gene Name : Sort1 sortilin 1 [ Rattus norvegicus ]
Official Symbol : SORT1
Synonyms : SORT1; sortilin 1; sortilin; NTR3; gp110; glycoprotein 110; Nt3; Nts3;
Gene ID : 83576
mRNA Refseq : NM_031767
Protein Refseq : NP_113955
UniProt ID : O54861

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All SORT1 Products

Required fields are marked with *

My Review for All SORT1 Products

Required fields are marked with *

0

Inquiry Basket

cartIcon
logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends