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Recombinant Rat Tek protein, His & GST-tagged

Cat.No. : Tek-537R
Product Overview : Recombinant Rat Tek aa. (Cys44~Glu341 (Accession # D3ZCD0)) fused with N-terminal His & GST tag was produced in E. coli cells.
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  • Gene Information
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Description : Mediates development of embryonic vasculature; plays a role in tumors and skin wounds.
Source : E. coli
Species : Rat
Tag : His & GST
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 63.6kDa
Protein length : Cys44~Glu341 (Accession # D3ZCD0)
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 8.
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4
Gene Name : Tek TEK receptor tyrosine kinase [ Rattus norvegicus (Norway rat) ]
Official Symbol : Tek
Synonyms : Tek; TEK receptor tyrosine kinase; Tie2; Tie-2; angiopoietin-1 receptor; TEK tyrosine kinase, endothelial; endothelial-specific receptor tyrosine kinase; tyrosine kinases that contain immunoglobulin-like loops and epidermal growth factor-similar domains 2
Gene ID : 89804
mRNA Refseq : NM_001105737.1
Protein Refseq : NP_001099207.1
UniProt ID : D3ZCD0

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does the TEK gene influence vascular development during embryogenesis, and what are the key molecular players involved? 09/26/2021

The TEK gene is crucial for vascular development during embryogenesis, coordinating with other genes and signaling pathways to ensure proper formation of the vascular system.

What role does the TEK gene play in pathological angiogenesis, particularly in diseases like cancer? 06/15/2020

The TEK gene is implicated in pathological angiogenesis in diseases like cancer, where dysregulation of TIE2 signaling can contribute to aberrant blood vessel formation.

How does the TEK gene contribute to the modulation of vascular permeability? 12/07/2019

The TEK gene, through TIE2 signaling, regulates vascular permeability by influencing the integrity of endothelial cell junctions and controlling the passage of molecules across blood vessels.

How does the TEK gene contribute to the maintenance of vascular quiescence, and what molecular processes are involved? 08/04/2019

The TEK gene contributes to the maintenance of vascular quiescence by suppressing endothelial cell activation and inflammation, preserving the stability of blood vessels.

How does the TEK gene participate in the regulation of immune responses in the context of vascular inflammation? 03/05/2018

The TEK gene, through TIE2 signaling, influences immune responses by modulating interactions between endothelial cells and immune cells during vascular inflammation.

Customer Reviews (3)

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Reviews
06/07/2020

    Outstanding service! Staff expertise helped us choose the perfect protein.

    10/31/2019

      Seamless delivery process—ordered, received, and ready for experiments.

      03/14/2018

        Courteous and efficient customer service made our purchase hassle-free.

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