Recombinant Rat WISP2 Protein

• Cat.No.: WISP2-6595R
• Product Overview: Recombinant Rat WISP2 full length or partial length protein was expressed.

Specification

• Species: Rat
• Source: Mammalian Cells
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Wisp2 WNT1 inducible signaling pathway protein 2 [ Rattus norvegicus ]
• Official Symbol: WISP2
• Gene ID: 29576
• mRNA Refseq: NM_031590.1
• Protein Refseq: NP_113778.1
• UniProt ID: Q9JHC6

Citation

IGF-I stimulates CCN5/WISP2 gene expression in pancreatic β-cells, which promotes cell proliferation and survival against streptozotocin.

Journal: Endocrinology    PubMed ID: 24552398    Data: 2014/6/16

Authors: Subrata Chowdhury, Xiao Wang, Jun-Li Liu

Article Snippet:An MTT cell viability assay was also performed in the presence or absence of the Akt inhibitor MK2206 (1 M) for 24 or 48 hours.An MTT cell viability assay was also performed in the presence or absence of the Akt inhibitor MK2206 (1 M) for 24 or 48 hours.. Finally, to establish the actions of CCN5 as an extracellular regulator, parental MIN6 cells were treated with rh CCN5/WISP2 protein (Creative BioMart), and its effects on cell proliferation were measured using an MTT assay and Akt phosphorylation.. CCN5 gene silencing using small interfering RNA (siRNA) The role of endogenous CCN5 on IGF-I–stimulated cell proliferation was investigated by RNA interference (RNAi)–mediated gene knockdown.CCN5 gene silencing using small interfering RNA (siRNA) The role of endogenous CCN5 on IGF-I–stimulated cell proliferation was investigated by RNA interference (RNAi)–mediated gene knockdown.