Recombinant Rhesus Macaque TNFSF10 Protein, His (Fc)-Avi-tagged
Cat.No. : | TNFSF10-4685R |
Product Overview : | Recombinant Rhesus Macaque TNFSF10 with His (Fc)-Avi tag was expressed and purified |
- Specification
- Gene Information
- Related Products
- Download
Source : | HEK293 |
Species : | Rhesus Macaque |
Tag : | His&Fc&Avi |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | ≥85% by SDS-PAGE |
Stability : | Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | PBS buffer |
Gene Name : | TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 [ Macaca mulatta (Rhesus monkey) ] |
Official Symbol : | TNFSF10 |
Synonyms : | TNFSF10; tumor necrosis factor ligand superfamily member 10; |
Gene ID : | 694451 |
mRNA Refseq : | NM_001266034 |
Protein Refseq : | NP_001252963 |
UniProt ID : | F6S9W7 |
Products Types
◆ Lysates | ||
TNFSF10-892HCL | Recombinant Human TNFSF10 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Reviews
- Q&As
Customer Reviews (3)
Write a reviewIts quality exceeding imagination, this experimental reagent becomes an indispensable tool for my experiments.
Through its employment, I am able to delve deeper into the essence of experimental principles and phenomena.
The exceptional performance of this experimental reagent significantly enhances the visibility of my research and amplifies my scholarly impact.
Q&As (7)
Ask a questionTNFSF10 protein holds great therapeutic potential as a target for various diseases. Studies have shown that utilizing its apoptosis-inducing ability, novel treatment strategies can be developed for cancer. Furthermore, TNFSF10 protein can be utilized in the design of immunotherapies to enhance immune responses. However, further research is needed to optimize TNFSF10 therapeutic strategies and gain a deeper understanding of its specific mechanisms in disease development.
The cellular source of TNFSF10 protein is diverse, including tumor cells, lymphocytes, monocytes, and dendritic cells. Additionally, some epithelial cells and endothelial cells also express TNFSF10 protein.
TNFSF10 protein has diverse physiological functions in tissue remodeling. It promotes inflammation, angiogenesis, and fibrosis processes. Moreover, TNFSF10 protein is involved in immune regulation and tissue repair, playing a crucial role in maintaining normal tissue functionality and structure.
TNFSF10 modulates multiple cellular processes beyond apoptosis induction. It can activate various signaling pathways, including the NF-κB pathway, which plays a key role in immune and inflammatory responses. TNFSF10 also regulates cell migration and invasion properties, affecting metastasis in some cancer types. Furthermore, TNFSF10 can promote immune cell activation and cytokine production, contributing to the regulation of the immune system.
TNFSF10 protein plays a significant role in cancer progression and metastasis. It induces apoptosis in tumor cells, inhibits tumor growth and metastasis, and regulates immune responses. Moreover, TNFSF10 protein interacts with other signaling pathways, participating in the modulation of the tumor microenvironment.
The transcriptional regulation of TNFSF10 gene involves various factors. Known regulators include transcription factors NF-κB, STAT3, and DNA methylation status. These factors modulate the expression levels of TNFSF10 gene, thereby influencing the production of TNFSF10 protein.
TNFSF10 protein interacts with its receptor, death receptor 5 (DR5), and triggers apoptosis pathway to induce cell death. Additionally, TNFSF10 protein also interacts with other ligands and receptors, such as TRAIL-R1 and TRAIL-R2, thereby regulating cell survival and death signaling transduction.
Ask a Question for All TNFSF10 Products
Required fields are marked with *
My Review for All TNFSF10 Products
Required fields are marked with *
Inquiry Basket