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Recombinant Rhesus monkey ANAPC15 Protein, His-tagged

Cat.No. : ANAPC15-320R
Product Overview : Recombinant Rhesus monkey ANAPC15 full length or partial length protein was expressed.
  • Specification
  • Gene Information
  • Related Products
Source : Mammalian Cells
Species : Rhesus monkey
Tag : His
Form : Liquid or lyophilized powder
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : >80%
Notes : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Storage : Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Storage Buffer : PBS buffer
Gene Name : ANAPC15 anaphase promoting complex subunit 15 [ Macaca mulatta (Rhesus monkey) ]
Official Symbol : ANAPC15
Synonyms : ANAPC15; C11orf51; C14H11orf51; uncharacterized protein LOC718333;
Gene ID : 718333
mRNA Refseq : NM_001193608
Protein Refseq : NP_001180537
MIM :
UniProt ID : F7GAV8

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (17)

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Can ANAPC15 be used as a diagnostic or prognostic marker for any diseases? 02/04/2023

Currently, ANAPC15 has not been established as a diagnostic or prognostic marker for any diseases. However, as research on ANAPC15 progresses, its potential as a biomarker may be explored in the future for certain diseases or disorders.

Are there any known interacting partners of ANAPC15? 10/29/2022

ANAPC15 is known to interact with other subunits of the APC/C complex, such as ANAPC2, ANAPC5, and ANAPC16. These interactions are crucial for the formation and functioning of the APC/C complex in regulating the cell cycle.

Are there any inherited disorders associated with ANAPC15 mutations? 01/28/2022

To date, there have been no known inherited disorders specifically associated with ANAPC15 mutations. However, it is worth noting that mutations in other subunits of the APC/C complex have been linked to developmental disorders and certain cancers. Therefore, it is possible that ANAPC15 mutations may also have implications in inherited disorders, but further research is required to establish any direct associations.

Can ANAPC15 be targeted for therapeutic purposes? 01/10/2022

As ANAPC15 is part of a larger protein complex, targeting it specifically may be challenging. However, the APC/C complex and its subunits, including ANAPC15, play critical roles in regulating the cell cycle, making them potential targets for therapeutic interventions in diseases such as cancer. Developing small molecules or targeted therapies that modulate the activity of the APC/C complex may have therapeutic potential, but more research is needed in this area.

Are there any known interactors or binding partners of ANAPC15? 12/22/2021

ANAPC15 has been shown to interact with several other subunits of the APC/C complex, such as ANAPC2, ANAPC5, and ANAPC16. These interactions are crucial for the assembly and stability of the APC/C complex. Additionally, ANAPC15 may interact with specific target proteins that are being ubiquitinated by the APC/C complex, although the specific binding partners of ANAPC15 in this context have not been extensively studied.

Can ANAPC15 expression be used as a biomarker for disease prognosis? 03/27/2021

At present, there is limited information on the potential use of ANAPC15 expression as a biomarker for disease prognosis. However, studies have indicated that dysregulation of other subunits of the APC/C complex is associated with poor prognosis in certain cancers. Further research is needed to determine whether ANAPC15 expression can serve as a reliable biomarker for disease prognosis in specific contexts.

Are there any known drugs or therapeutic interventions that affect ANAPC15 function? 12/02/2020

As of now, there are no known drugs or therapeutic interventions that specifically target ANAPC15. However, there are drugs that indirectly affect the function of the APC/C complex and, consequently, may impact ANAPC15's activity. For example, certain chemotherapeutic drugs used in cancer treatment, such as taxanes and platinum-based compounds, can affect cell cycle progression indirectly through the APC/C complex.

How is ANAPC15 expression regulated? 04/15/2020

The regulation of ANAPC15 expression is not well-studied at the moment. However, it is likely that the expression of ANAPC15 is controlled by various mechanisms, including transcriptional regulation, post-transcriptional modifications, and protein stability.

Are there any diseases or conditions associated with ANAPC15 dysregulation? 02/02/2020

Currently, there is limited research on the specific role of ANAPC15 dysregulation in diseases or conditions. However, dysregulation of other subunits of the APC/C complex has been implicated in various diseases, including cancer, neurodegenerative disorders, and developmental abnormalities. Therefore, it is plausible that ANAPC15 dysregulation may contribute to the pathogenesis of similar conditions, but further research is needed to establish any direct associations.

Are there any known allelic variations in ANAPC15? 10/15/2018

Existing literature does not currently report any known allelic variations or polymorphisms in ANAPC15. However, ongoing research efforts may uncover genetic variations in ANAPC15 in different populations, and larger-scale studies are needed to comprehensively assess the genetic diversity within this gene.

Does ANAPC15 have any role in cancer development? 10/07/2018

While ANAPC15 has not been extensively studied in the context of cancer, dysregulation or mutations in other subunits of the APC/C complex have been associated with the development and progression of various cancers. Therefore, it is possible that ANAPC15 dysregulation or mutations may also contribute to cancer development, but further research is needed to establish a direct link.

Is ANAPC15 involved in DNA repair processes? 07/12/2018

ANAPC15 is primarily known for its role in regulating the cell cycle through the APC/C complex. While it is not directly involved in DNA repair processes, the proper progression of the cell cycle, which ANAPC15 contributes to, is crucial for efficient DNA repair. Dysregulation of the cell cycle can lead to genomic instability and impaired DNA repair mechanisms, potentially contributing to the development of certain diseases, including cancer.

How does ANAPC15 influence the ubiquitin-proteasome system? 05/11/2018

ANAPC15 is a subunit of the anaphase-promoting complex/cyclosome (APC/C), which is responsible for tagging specific proteins with ubiquitin for degradation by the proteasome. ANAPC15 helps to form the core structure of the APC/C complex and is involved in the recognition and binding of target proteins. Through its interaction with other subunits of the complex, ANAPC15 facilitates the ubiquitination of target proteins, leading to their subsequent degradation by the proteasome.

How is ANAPC15 regulated or modified? 10/25/2017

There is limited information available regarding the regulation or modification of ANAPC15. However, like other subunits of the APC/C complex, ANAPC15 is likely subjected to various post-translational modifications, such as phosphorylation, acetylation, or methylation, which can affect its stability and function. Future research may uncover more regulatory mechanisms and modifications that impact ANAPC15.

Is ANAPC15 studied in animal models? 05/12/2017

Currently, there is limited research on ANAPC15 itself, and therefore, the availability of animal models specifically targeting ANAPC15 is unknown. However, there are animal models available to study other subunits of the APC/C complex, which can indirectly inform our understanding of ANAPC15's function.

Is there any known involvement of ANAPC15 in cellular apoptosis or programmed cell death? 04/19/2017

There is currently no direct evidence to suggest that ANAPC15 is involved in cellular apoptosis or programmed cell death. However, given its role in cell cycle regulation, it is possible that ANAPC15 indirectly affects these processes by influencing the stability and degradation of the proteins involved in apoptosis.

Can mutations or dysregulation in ANAPC15 cause any diseases or disorders? 06/19/2016

Currently, no specific diseases or disorders have been directly linked to mutations or dysregulation in ANAPC15. However, dysfunctions in other subunits of the APC/C complex have been associated with various diseases and cancer. Further research is needed to explore if ANAPC15 dysregulation could have similar implications.

Customer Reviews (4)

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Reviews
01/19/2023

    They ensure a reliable and consistent supply of ANAPC15 protein, minimizing any potential disruptions in my experimental workflow.

    07/18/2020

      With their assistance, I am confident in overcoming challenges, producing robust results, and advancing our understanding of ANAPC15 protein and its biological significance.

      12/16/2019

        In addition to the impeccable protein quality, the manufacturer provides excellent technical support that can effectively address any challenges I may encounter during my experiments.

        03/26/2019

          This reliable supply chain management assures that I have uninterrupted access to the protein, allowing me to plan and conduct my experiments without concern for availability issues.

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