Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Saccharomyces Cerevisiae KAE1 Protein (1-386 aa), His-SUMO-tagged

Cat.No. : KAE1-1768S
Product Overview : Recombinant Saccharomyces Cerevisiae (strain ATCC 204508/S288c) (Baker's yeast) KAE1 Protein (1-386 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Protein Description: Full Length.
  • Specification
  • Gene Information
  • Related Products
Description : Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
Source : E. coli
Species : Saccharomyces Cerevisiae
Tag : His-SUMO
Form : Tris-based buffer,50% glycerol
Molecular Mass : 46.7 kDa
Protein length : 1-386 aa
AA Sequence : MVNLNTIPPKNGRDYYIALGLEGSA NKLGVGIVKHPLLPKHANSDLSYDC EAEMLSNIRDTYVTPPGEGFLPRDT ARHHRNWCIRLIKQALAEADIKSPT LDIDVICFTKGPGMGAPLHSVVIAA RTCSLLWDVPLVGVNHCIGHIEMGR EITKAQNPVVLYVSGGNTQVIAYSE KRYRIFGETLDIAIGNCLDRFARTL KIPNEPSPGYNIEQLAKKAPHKENL VELPYTVKGMDLSMSGILASIDLLA KDLFKGNKKNKILFDKTTGEQKVTV EDLCYSLQENLFAMLVEITERAMAH VNSNQVLIVGGVGCNVRLQEMMAQM CKDRANGQVHATDNRFCIDNGVMIA QAGLLEYRMGGIVKDFSETVVTQKF RTDEVYAAWRD
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with reconstitution instruction is sent along with the products.
Synonyms : KAE1; Kinase-associated endopeptidase 1 N6-L-threonylcarbamoyladenine synthase Short name: t(6)A synthase t(6)A37 threonylcarbamoyladenosine biosynthesis protein KAE1 tRNA threonylcarbamoyladenosine biosynthesis protein KAE1;
UniProt ID : P36132
Synonyms : KAE1; Kinase-associated endopeptidase 1 N6-L-threonylcarbamoyladenine synthase Short name: t(6)A synthase t(6)A37 threonylcarbamoyladenosine biosynthesis protein KAE1 tRNA threonylcarbamoyladenosine biosynthesis protein KAE1;
UniProt ID : P36132

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All KAE1 Products

Required fields are marked with *

My Review for All KAE1 Products

Required fields are marked with *

0

Inquiry Basket

cartIcon
logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends