Recombinant SARS Coronavirus Spike Glycoprotein Mosaic (S1) protein

• Cat.No.: Spike-203V
• Product Overview: Recombinant SARS Coronavirus Spike Glycoprotein Mosaic (S1) protein was expressed in E.coli. It contains the N-terminal section of the Spike protein 12-53, 90-115, 171-203 amino acids immunodominant regions.

Specification

• Species: SARS-CoV
• Source: E.coli
• Protein Length: 12-53;90-115;171-203 a.a.
• Description: Spike protein S1: Attaches the virion to the cell membrane by interacting with host receptor, initiating the infection (By similarity). Binding to human ACE2 and CLEC4M/DC-SIGNR receptors and internalization of the virus into the endosomes of the host cell induces conformational changes in the S glycoprotein. Proteolysis by cathepsin CTSL may unmask the fusion peptide of S2 and activate membranes fusion within endosomes.
• Form: Liquid. 25mM Tris-HCl, 0.4% sarcosyl, 0.25% Triton X-100 and 50% glycerol.
• Molecular Mass: 38 kDa
• Purity: >95% as determined by 10% PAGE (Coomassie staining).
• Applications: ELISA, Western blot.
• Storage: Upon arrival, storeat below -18 centigrade.
• Shipping: Dry Ice.
• Warning: For Research Use Only.

Gene Information

• Synonyms: sars2; E2; sars3a