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Recombinant Sheep TGFB1 protein, His & GST-tagged

Cat.No. : TGFB1-529S
Product Overview : Recombinant Sheep TGFB1 aa. (Ala279~Ser390 (Accession # P50414)) fused with N-terminal His & GST tag was produced in E. coli cells.
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  • Gene Information
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Source : E. coli
Species : Sheep
Tag : His & GST
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 45.2kDa
Protein length : Ala279~Ser390 (Accession # P50414)
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 7.2.
Applications : SDS-PAGE; WB; ELISA; IP
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : TGFB1 transforming growth factor beta 1 [ Ovis aries (sheep) ]
Official Symbol : TGFB1
Synonyms : TGFB1; transforming growth factor beta-1; TGF-beta 1; transforming growth factor, beta 1 (Camurati-Engelmann disease)
Gene ID : 443417
mRNA Refseq : NM_001009400.1
Protein Refseq : NP_001009400.1
UniProt ID : P50414

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How is TGFB1 involved in bone remodeling? 08/04/2020

TGFB1 stimulates the activity of cells involved in bone formation (osteoblasts) and plays a role in regulating bone resorption by influencing osteoclast function.

Are there any side effects associated with therapies targeting TGFB1? 10/09/2019

Potential side effects of anti-TGFB1 therapies may include immune system suppression, gastrointestinal issues, and skin reactions.

Can TGFB1 be used as a biomarker for certain diseases? 04/11/2017

TGFB1 levels have been studied as potential biomarkers for diseases like cancer and fibrosis, aiding in diagnosis and monitoring disease progression.

In what ways does TGFB1 influence wound healing? 05/15/2016

TGFB1 plays a critical role in wound healing by stimulating the formation of new blood vessels, promoting the production of extracellular matrix, and aiding in the migration of cells to the wound site.

How does TGFB1 contribute to fibrosis? 05/06/2016

TGFB1 can induce the production of excessive extracellular matrix proteins, leading to tissue scarring and fibrosis in organs such as the liver, lung, and kidneys.

Customer Reviews (3)

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Reviews
11/16/2021

    The impressive performance of the TGFB1 protein both in ELISA assays and protein electron microscopy structure analysis makes it a highly versatile and recommended choice for scientists across various disciplines.

    03/01/2020

      Its reliability and efficacy in generating high-quality data make it an indispensable tool in the quest for unraveling the mysteries of protein structure and function.

      07/16/2018

        The TGFB1 protein's excellent performance in ELISA ensures accurate and reproducible results, enhancing the reliability of experimental data.

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