| Species : |
Pig |
| Source : |
Yeast |
| Tag : |
Non |
| Description : |
This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. Specifically, chemokines attract lymphocytes to sites of infection or damage. This protein binds to several chemokine receptors including chemokine binding protein 2 (CCBP2 or D6) and chemokine (C-C motif) receptor 5 (CCR5). |
| Sequences Of Amino Acids : |
APLGADTPTA CCFSYTSRQL PRKFVADYFE TSSQCSKPGV IFQTKKGREV CANPEDAWVQ EYISDLELNA. |
| Formulation/Reconstitution : |
Lyophilized. Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein. |
| Purity : |
>95% as visualized by SDS-PAGE analysis. |
| Purification : |
Ion-exchange chromatography. |
| Biological Activity : |
The biological activity of recombinant swine CCL3L1 was determined in a chemotaxis assay using a Boyden chamber with freshly isolated swine PBMC monocytes using a Percoll gradient enrichment method. Biological activity typically peaks at 100 ng/mL. |
| Storage : |
Stable for up to twelve months from date of receipt at -20°C. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles. |
| Pathways : |
Chemokine signaling pathway; Cytokine-cytokine receptor interaction |