Recombinant Zebrafish ATXN1A
Cat.No. : | ATXN1A-3958Z |
Product Overview : | Recombinant Zebrafish ATXN1A full length or partial length protein was expressed. |
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Source : | Mammalian Cells |
Species : | Zebrafish |
Tag : | His |
Form : | Liquid or lyophilized powder |
Endotoxin : | < 1.0 eu per μg of the protein as determined by the LAL method. |
Purity : | >80% |
Notes : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
Storage : | Store it at +4 oC for short term. For long term storage, store it at -20 oC~-80 oC. |
Storage Buffer : | PBS buffer |
Gene Name : | atxn1a ataxin 1a [ Danio rerio (zebrafish) ] |
Official Symbol : | ATXN1A |
Gene ID : | 557340 |
mRNA Refseq : | NM_001044826 |
Protein Refseq : | NP_001038291 |
UniProt ID : | Q1L966 |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionATXN1A gene is associated with spinocerebellar ataxia type 1 (SCA1). SCA1 is an inherited neurological disorder caused by mutations in the ATXN1A gene.
The expression of ATXN1A gene is affected by a variety of regulatory mechanisms, including the binding of transcriptional regulators, epigenetic modification, and regulation by non-coding RNA.
The ATXN1A mutation leads to the expansion of glutamine repeats in the ATXN1A protein, resulting in the formation of abnormal polyglutamic acid protein. The abnormal accumulation of this protein can lead to abnormal function and degenerative changes of nerve cells, triggering the occurrence of SCA1.
The protein encoded by the ATXN1A gene plays an important role in the nervous system, involving in cell cycle regulation, transcriptional regulation, and protein degradation.
This gene is expressed in several tissues, but its expression is higher in the central nervous system, especially in the cerebellum and spinal cord.
Yes, the ATXN1A gene interacts with other genes to form a complex regulatory network. For example, ATXN1A protein interacts with Capicua (CIC) protein to participate in transcriptional regulation.
Customer Reviews (3)
Write a reviewThe high activity of ATXN1A ensures its stable performance, making it a preferred choice for researchers.
The wide applicability of ATXN1Aeins makes them play a key role in many fields of research and promotes the progress of science.
This high stability of ATXN1A ensures its stable properties, making it a preferred choice for researchers.
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