Recombinant Zebrafish il1b Protein, His-tagged
Cat.No. : | il1b-2298Z |
Product Overview : | Recombinant Zebrafish il1b Protein (Met1-Ile273) with a N-His tag was expressed in E. coli. |
- Specification
- Gene Information
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Description : | Predicted to enable cytokine activity. Acts upstream of or within several processes, including fin regeneration; leukocyte chemotaxis; and response to bacterium. Predicted to be located in cytosol; extracellular region; and lysosome. Predicted to be active in extracellular space. Is expressed in several structures, including digestive system; gill; heart; male organism; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); blood platelet disease (multiple); eye disease (multiple); gastrointestinal system cancer (multiple); and lung disease (multiple). Orthologous to human IL1B (interleukin 1 beta). |
Source : | E. coli |
Species : | Zebrafish |
Tag : | N-His |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 34.1 kDa Accurate Molecular Mass: 37 kDa |
Protein length : | Met1-Ile273 |
Endotoxin : | <1.0 EU per 1µg (determined by the LAL method). |
Purity : | > 90% |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Storage Buffer : | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
Reconstitution : | Reconstitute in PBS or others. |
Gene Name : | il1b interleukin 1, beta [ Danio rerio (zebrafish) ] |
Official Symbol : | il1b |
Synonyms : | il1b; interleukin 1, beta; il1-b; zgc:111873; interleukin-1 beta interlukin-1 beta |
Gene ID : | 405770 |
mRNA Refseq : | NM_212844 |
Protein Refseq : | NP_998009 |
UniProt ID : | E6N152 |
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IL1B-4503M | Recombinant Mouse IL1B Protein, His (Fc)-Avi-tagged | +Inquiry |
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IL1B-364I | Active Recombinant Pig IL1B Protein (154 aa) | +Inquiry |
◆ Lysates | ||
IL1B-853HCL | Recombinant Human IL1B cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionInflammasome assembly initiated by IL-1β is deciphered using techniques like co-immunoprecipitation, proximity ligation assays, and super-resolution microscopy.
IL-1β's priming of immune cells is dissected through flow cytometry, RNA sequencing, and chromatin immunoprecipitation, revealing its epigenetic and transcriptional effects.
Mass spectrometry-based phosphoproteomics deciphers IL-1β's post-translational modifications, revealing regulatory sites crucial for its activation and signaling.
Bioinformatics tools integrate multi-omics data to provide a comprehensive understanding of IL-1β's roles, revealing its intricate contributions to health and disease.
ChIP-seq and DNA methylation profiling uncover IL-1β's epigenetic impact on target genes, shedding light on its role in shaping chronic inflammatory states.
IL-1β's interactions with downstream effectors are unveiled using dual-luciferase reporter assays, surface plasmon resonance, and co-crystallization studies.
Network analysis integrates omics data to unravel IL-1β's intricate cross-talk with other cytokines, mapping out complex regulatory loops in inflammation.
IL-1β's impact on the tumor microenvironment is studied using intravital microscopy, 3D culture models, and single-cell RNA sequencing to capture dynamic cell behavior.
CRISPR-Cas9 screening identifies IL-1β's non-canonical signaling mediators through functional genomics, revealing alternative pathways in cellular responses.
Single-cell RNA sequencing unveils IL-1β's context-specific responses, exposing cell type-specific signaling and gene expression patterns.
Customer Reviews (3)
Write a reviewEffective in inflammation studies.
High specificity.
Suitable for cytokine assays.
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