CCL7

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CCL7

Official Full Name chemokine (C-C motif) ligand 7
Background Murine MCP-3, also known as Monocyte Chemotactic Protein 3 or C-C Motif Chemokine 7, is a 97 amino acid cytokine protein expressed from the Ccl7 gene located on chromosome 11. After initial synthesis and translocation, the 23 residue signal sequence is cleaved, allowing for the 74 residue MCP-3 peptide to properly fold and mature. MCP-3 is essentially a chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Moreover, the monomeric member of the intercrine beta (chemokine C-C) family tends to augment monocyte anti-tumor activity as well.
Synonyms RP23-350G1.4; MCP-3; Scya7; fic; marc; mcp3; C-C motif chemokine 7; RANTES/sis homolog; intercrine/chemokine MARC; monocyte chemoattractant protein 3; monocyte chemotactic protein 3; small inducible cytokine A7; small-inducible cytokine A7
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • CHO
    • E.coli
    • HEK293
    • Human
    • Human Cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • Biotin
    • Fc
    • GST
    • His
    • T7
    • N/A
    • Strep II
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CCL7-0643H Recombinant Human CCL7 Protein, GST-Tagged Wheat Germ GST
    Human CCL7-10852H Recombinant Human CCL7, His-tagged E.coli His
    Human CCL7-132H Recombinant Human CCL7, biotinylated E.coli Biotin
    Human CCL7-170HCL Recombinant Human CCL7 lysate HEK293 N/A
    Human CCL7-194H Recombinant Human CCL7 protein E.coli N/A
    Human CCL7-199H Recombinant Human Chemokine (C-C Motif) Ligand 7, His-tagged Human His
    Human CCL7-286H Recombinant Human CCL7 protein E.coli N/A
    Human CCL7-29150TH Recombinant Human CCL7 E.coli N/A
    Human CCL7-291H Recombinant Human CCL7, StrepII-tagged Human Cell Strep II
    Human CCL7-36H Recombinant Human Chemokine (C-C Motif)Ligand 7 E.coli N/A
    Human CCL7-383H Recombinant Human Chemokine (C-C Motif) Ligand 7, MIgG2a Fc-tagged CHO Fc
    Human CCL7-384H Recombinant Human Chemokine (C-C Motif) Ligand 7, HIgG1 Fc-tagged, mutant CHO Fc
    Human CCL7-385H Recombinant Human Chemokine (C-C Motif) Ligand 7, HIgG1 Fc-tagged CHO Fc
    Human CCL7-627H Recombinant Human CCL7, His tagged E.coli His
    Human CCL7-696H Recombinant Human CCL7 protein, GST-tagged E.coli GST
    Mouse Ccl7-287M Recombinant Mouse Chemokine (C-C motif) Ligand 7 E.coli N/A
    Mouse CCL7-46M Recombinant Mouse chemokine (C-C motif) ligand 7 (CCL7) E.coli N/A
    Mouse Ccl7-618M Recombinant Mouse Ccl7 protein E.coli N/A
    Mouse Ccl7-883M Recombinant Mouse Ccl7 Protein, His-tagged E.coli His
    Rat CCL7-1216R Recombinant Rat CCL7 Protein Mammalian Cell His
    Rat Ccl7-635R Recombinant Rat Ccl7 protein E.coli N/A
    Rat Ccl7-697R Recombinant Rat Ccl7 protein, His & T7-tagged E.coli His/T7

    CCL7 involved in several pathways and played different roles in them. We selected most pathways CCL7 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCL7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction BMPR1BB; IL22; HGF; IL23; CXCR3; IRX1; IL-8; CCR9A; LIF; TNFRSF6B
    Chemokine signaling pathway RAP1B; CXCR3; XCL1; WAS; CXCL11; CCL16; CXCR5; RAC1; CCL4L1; PPBP

    CCL7 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by CCL7 itself. We selected most functions CCL7 had, and list some proteins which have the same functions with CCL7. You can find most of the proteins on our site.

    Function Related Protein
    CCR1 chemokine receptor binding CCL7; CCL5; CREB3; CCL3; CCL4; CCL23
    CCR2 chemokine receptor binding Ccl12; CCL7; CCL2
    chemokine activity PF4V1; CCL14; CCL7; CCL27; CCL39.1; CXCL20; Ccl12; CCL25; CXCL13; CKLF
    heparin binding CHRD; COMP; PCSK6; CCL2; SERPINA5; PTN; THBS1; REG4; FSTL1; SERPINA10
    protein binding ZBTB16; CAMK2A; ATP7B; MKRN3; ODC1; ARL14; DHX16; DTX2; C21orf2; NDEL1

    CCL7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCL7 here. Most of them are supplied by our site. Hope this information will be useful for your research of CCL7.

    UBQLN1; UBQLN1; AES; FEZ1

    Kitase, Y; Lee, S; et al. CCL7 Is a Protective Factor Secreted by Mechanically Loaded Osteocytes. JOURNAL OF DENTAL RESEARCH 93:1108-1115(2014).
    Mercer, PF; Williams, AE; et al. Proteinase-Activated Receptor-1, CCL2, and CCL7 Regulate Acute Neutrophilic Lung Inflammation. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY 50:144-157(2014).

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