Recombinant Rat Ccl7 protein

Cat.No. : Ccl7-635R
Product Overview : Recombinant Rat Ccl7 protein was expressed in Escherichia coli.
  • Specification
  • Gene Information
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Description : Rat CCL7, belonging to the CC chemokine family, is also named as MCP-3, because the sequence comparison suggested that the rat CCL7 is a homologue of the human MCP-3 and is postulated the rat MCP-3. The MCP-3 protein family signals through CCR2 expect MCP-1 and possess cross-reacts across species. CCL7/MCP3 has chemotactic functions for monocytes and eosinophils, but not for neutrophils. Additionally, it can activated NK cells as well as CD4+ and CD8+ T lymphocytes. CCL7 was found to interact with MMP2.
Source : E.coli
Species : Rat
Form : Lyophilized from a 0.2μm filtered concentrated solution in 2 × PBS, pH 7.4.
Bio-activity : Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human monocytes is in a concentration range of 10-100 ng/ml.
Molecular Mass : Approximately 8.5 kDa, a single non-glycosylated polypeptide chain containing 74 amino acids.
Protein length : 74
AA Sequence : QPDGTNSSTCCYVKKQKIPKRNLKS YRKITSSRCPWEAVIFKTKKGMEVC AEAHQKWVEEAIAYLDMKTSTPKP
Endotoxin : Less than 1 EU/µg of rRtMCP-3/CCL7 as determined by LAL method.
Purity : >95% by SDS-PAGE and HPLC analysis.
Storage : Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution : We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤-20 centigrade. Further dilutions should be made in appropriate buffered solutions.
Gene Name : Ccl7
Official Symbol : Ccl7
Synonyms : CCL7; chemokine (C-C motif) ligand 7; C-C motif chemokine 7; MCP-3; chemotactic protein-3; small-inducible cytokine A7; monocyte chemotactic protein 3; monocyte chemoattractant protein 3;
Gene ID : 287561
mRNA Refseq : NM_001007612
Protein Refseq : NP_001007613
UniProt ID : Q9QXY8

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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