Recombinant Human CCL7 protein

• Cat.No.: CCL7-194H
• Product Overview: Recombinant Human CCL7 was expressed in E. coli.

Specification

• Description: Essentially a chemo-attractant, CCL7 signals through CCR receptors 1, 2 and 3. CCL7 can attract and activate monocytes, natural killer cells, T cells, and immature dendritic cells. CCL7 has also been shown to attract esosinophiles and induce histamine secretion from basophils.
• Source: E. coli
• Species: Human
• Form: Lyophilized from a 0.2 μm filtered solution of PBS
• Molecular Mass: 9.2 kDa
• Endotoxin: <1.0 EU/μg of recombinant protein as determined by the LAL method.
• Purity: 95%
• Applications: Cell Assay
• Storage: The lyophilized protein is stable for at least one year from date of receipt at -70 centigrade. Upon reconstitution, this cytokine can be stored in working aliquots at 2 centigrade- 8 centigrade for one month, or at -20 centigrade for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
• Reconstitution: Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin

Gene Information

• Gene Name: CCL7 chemokine (C-C motif) ligand 7 [ Homo sapiens ]
• Official Symbol: CCL7
• Synonyms: CCL7; chemokine (C-C motif) ligand 7; SCYA6, SCYA7, small inducible cytokine A7 (monocyte chemotactic protein 3); C-C motif chemokine 7; FIC; MARC; MCP 3; MCP3; monocyte chemoattractant protein 3; monocyte chemotactic protein 3; NC28; small-inducible cytokine A7; small inducible cytokine A7 (monocyte chemotactic protein 3); MCP-3; SCYA6; SCYA7; MGC138463; MGC138465
• Gene ID: 6354
• mRNA Refseq: NM_006273
• Protein Refseq: NP_006264
• MIM: 158106
• UniProt ID: P80098
• Chromosome Location: 17q11.2-q12
• Pathway: Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; GPCR ligand binding, organism-specific biosystem
• Function: CCR1 chemokine receptor binding; chemokine activity; heparin binding