cxcl16
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  • Official Full Name
  • chemokine (C-X-C motif) ligand 16
  • Background
  • Chemokine (C-X-C motif) ligand 16 (CXCL16), also known as SR-PSOX, is a transmembrane protein that facilitates uptake of low density lipoproteins by macrophages, resulting in foam cell formation. CXCL16 is found in liver tissue2 and influences the uptake, subcellular localization, and cytokine profile induced by D oligonucleotides. 3 CXCL16 may play a pro- inflammatory role in Inflammatory Bowel Disease (IBD), particularly Crohns disease.
  • Synonyms
  • chemokine (C-X-C motif) ligand 16; SRPSOX; CXCLG16; SR-PSOX; CXCL16; CXC chemokine ligand 16; Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein; Small-inducible cytokine B16; Transmembrane chemokine CXCL16
Cat.#:CXCL16-1108HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CXCL16 Protein (Met1-Thr224), His-tagged
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Cat.#:Cxcl16-347MTag:His
Source (Host):YeastSpecies:Mouse
Product nameRecombinant Mouse Cxcl16 Protein, His-tagged
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Cat.#:CXCL16-2164HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CXCL16 Protein, GST-tagged
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Cat.#:CXCL16-253CTag:
Source (Host):E. coliSpecies:Cynomolgus
Product nameRecombinant Cynomolgus CXCL16 Protein
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Cat.#:CXCL16-372HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Chemokine (C-X-C motif) Ligand 16
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Cat.#:Cxcl16-484MTag:His
Source (Host):NS0Species:Mouse
Product nameRecombinant Mouse Chemokine (C-X-C motif) Ligand 16, His-tagged
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Cat.#:CXCL16-11721HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CXCL16, GST-tagged
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Cat.#:CXCL16-330HTag:His
Source (Host):NSO cellsSpecies:Human
Product nameRecombinant Human CXCL16, His-tagged
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Cat.#:CXCL16-7648HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CXCL16 protein, His & T7-tagged
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Cat.#:CXCL16-82HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Chemokine (C-X-C motif) Ligand 16
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Cat.#:Cxcl16-153MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Cxcl16, His tagged
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Cat.#:Cxcl16-7649MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Cxcl16 protein, His & T7-tagged
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Cat.#:Cxcl16-85MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Chemokine (C-X-C Motif) Ligand 16
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Cat.#:CXCL16-1083RTag:His
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat CXCL16 Protein, His-tagged
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Cat.#:CXCL16-1688RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CXCL16 Protein
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Cat.#:Cxcl16-7441RTag:Fc
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Cxcl16, Fc tagged
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Cat.#:Cxcl16-7650RTag:His/T7
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Cxcl16 protein, His & T7-tagged
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Cat.#:CXCL16-178CTag:Fc
Source (Host):HEK293Species:Canine
Product nameRecombinant Canine CXCL16, Fc tagged
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Cat.#:CXCL16-259CTag:Fc
Source (Host):HEK293Species:Canine
Product nameRecombinant Canine CXCL16, His tagged
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Cat.#:CXCL16-2545MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse CXCL16 cell lysate
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Cat.#:CXCL16-1414RCLTag:
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat CXCL16 cell lysate
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Cat.#:CXCL16-842CCLTag:
Source (Host):HEK293Species:Canine
Product nameRecombinant Canine CXCL16 cell lysate
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Involved Pathway

Cxcl16 involved in several pathways and played different roles in them. We selected most pathways Cxcl16 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Cxcl16 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine-cytokine receptor interaction
TNFRSF11A; CCL21B; IFNA6; CCL19B; GM13304; AMH; XCL2; IFNAR1; IFNG; IFNAR2
Chemokine signaling pathway
GNG10; VAV1; CCR6; GM1987; GNG7; CCR10; CXCL2; GNG5; CCL28; CCR3

Protein Function

Cxcl16 has several biochemical functions, for example, chemokine activity, low-density lipoprotein receptor activity, scavenger receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Cxcl16 itself. We selected most functions Cxcl16 had, and list some proteins which have the same functions with Cxcl16. You can find most of the proteins on our site.
Function
Related Protein
Function chemokine activity
Related Protein CCL21; CCL18; CXCL2; CCL2; CCL34B.9; CXCL12; CCL34B.4; CCL20B; CCL19B; CXCL9
Function low-density lipoprotein receptor activity
Related Protein LRP12; LDLR; CXCL16; OLR1; VLDLR; LRP6
Function scavenger receptor activity
Related Protein TINAGL1; SCART1; TMPRSS2; VTNB; CFI; LOXL2A; SCARA5; SCARF2; PRSS12; C8orf84

Cxcl16 Related Articles

Wehr, A; Baeck, C; et al. Pharmacological Inhibition of the Chemokine CXCL16 Diminishes Liver Macrophage Infiltration and Steatohepatitis in Chronic Hepatic Injury. PLOS ONE 9:-(2014).
Wang, L; Sun, SZ; et al. oxLDL-Induced Lipid Accumulation in Glomerular Podocytes: Role of IFN-gamma, CXCL16, and ADAM10. CELL BIOCHEMISTRY AND BIOPHYSICS 70:529-538(2014).

Cxcl16 Related Gene Family

Chemokines Cytokines