efnb1
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  • Official Full Name
  • ephrin-B1
  • Background
  • The protein encoded by this gene is a type I membrane protein and a ligand of Eph-related receptor tyrosine kinases. It may play a role in cell adhesion and function in the development or maintenance of the nervous system.
  • Synonyms
  • EFNB1; ephrin-B1; CFNS, craniofrontonasal syndrome (craniofrontonasal dysplasia) , EPLG2; Elk L; LERK2; CFND; CFNS; Craniofrontonasal syndrome (craniofrontonasal dysplasia); EFL 3; EFL-3; EFL3; EFNB1_HUMAN; ELK ligand; ELK-L; Eph related receptor tyrosine kinase ligand 2; EPH-related receptor tyrosine kinase ligand 2; EPLG2; LERK 2; LERK-2; Ligand of eph related kinase 2; MGC8782; OTTHUMP00000023456; ligand of eph-related kinase 2
Cat.#:EFNB1-001HTag:His|HIgG
Source (Host):Insect cellSpecies:Human
Product nameRecombinant Human EFNB1 Protein, hIgG-His-tagged
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Cat.#:EFNB1-1383HTag:Myc|DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human EFNB1 Protein, MYC/DDK-tagged
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Cat.#:EFNB1-3102HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human EFNB1 Protein, GST-tagged
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Cat.#:EFNB1-2237HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human EFNB1, His tagged
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Cat.#:EFNB1-2239HTag:Fc|His
Source (Host):HEK293Species:Human
Product nameRecombinant Human EFNB1, Fc-His tagged
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Cat.#:EFNB1-3635HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human EFNB1, His-tagged
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Cat.#:Efnb1-181MTag:Fc Chimera
Source (Host):NSO cellsSpecies:Mouse
Product nameRecombinant Mouse Efnb1, Fc Chimera
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Cat.#:Efnb1-4049MTag:Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Efnb1, Fc tagged
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Cat.#:Efnb1-4050MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Efnb1, His tagged
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Cat.#:EFNB1-1077RTag:His
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat EFNB1 Protein, His-tagged
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Cat.#:Efnb1-7434RTag:Fc
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Efnb1, Fc tagged
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Cat.#:EFNB1-1394RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey EFNB1 Protein, His-tagged
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Cat.#:EFNB1-6592CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken EFNB1
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Cat.#:EFNB1-9316ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish EFNB1
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Cat.#:EFNB1-152HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Ephrin-B1
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Cat.#:Efnb1-1733MTag:N/A
Source (Host):NS0Species:Mouse
Product nameRecombinant Mouse Ephrin B1
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Cat.#:EFNB1-2537HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human EFNB1 cell lysate
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Cat.#:EFNB1-2152MCLTag:N/A
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse EFNB1 cell lysate
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Cat.#:EFNB1-1515RCLTag:N/A
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat EFNB1 cell lysate
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Involved Pathway

EFNB1 involved in several pathways and played different roles in them. We selected most pathways EFNB1 participated on our site, such as Axon guidance, Developmental Biology, EPH-Ephrin signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with EFNB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Axon guidance
NETO2; SLIT1; RASGRP1; RHOD; Ntng2; EFNA1B; ARPC3; ACTR2; ITSN1; CHL1
Developmental Biology
RASGEF1A; COL6A1; KDR; ARPC3; PHB; EVL; FGF20A; LGI4; CARM1; EFNA1
EPH-Ephrin signaling
EFNB3B; EFNB2; EFNB3; EPHB3A; ARHGEF28; MYL12B; ARPC1A; ARPC4; ACTR3; EFNA3
EPH-ephrin mediated repulsion of cells
EFNA2; EFNA4; EFNB2A; EFNB3; AP2A2; EFNA5; EFNB2; AP2B1; EFNA1B; EFNB1
EPHB forward signaling
EFNB1; GRB7; EFNB3; ITSN1; EFNA5; EFNB2
EPHB-mediated forward signaling
ARPC4; ACTR2B; EPHB4A; ARPC3; ARPC1A; ARPC5; CFL1; EFNB3; ARPC1B; ARPC2
Ephrin B reverse signaling
PTPN13; EFNB2; EFNB1
Ephrin signaling
EFNB3; EFNB1; EPHB3A; EFNB2; EPHB4B; MYL12A; EFNB3B; EFNB2A; SDCBP; EPHB4A

Protein Function

EFNB1 has several biochemical functions, for example, ephrin receptor binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EFNB1 itself. We selected most functions EFNB1 had, and list some proteins which have the same functions with EFNB1. You can find most of the proteins on our site.
Function
Related Protein
Function ephrin receptor binding
Related Protein SIPA1L1; EFNB3B; EFNA2; EFNA3B; EFNA5B; CDK5; EFNA1; EFNB1; EFNB3; SRC
Function protein binding
Related Protein NLRC5; MEGF6; LEPR; TUB; HNF4A; CIR1; SHARPIN; TNFSF14; GSTO1; RNF113A

Interacting Protein

EFNB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EFNB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of EFNB1.
ERBB2; Erbb2; Sdcbp; MYC; YWHAQ; CUL3; Pick1; Grip1; CAPN10