Recombinant Human EFNB1, His-tagged

• Cat.No.: EFNB1-3635H
• Product Overview: Recombinant human EFNB1 protein, fused to His-tag at N-terminus, was expressed in E.coli (28-237aa).

Specification

• Species: Human
• Source: Human
• Tag: His
• Description: Ephrin-B1, also known as EFNB1, belongs to the Eph family. Ephrins, which act as ligands for Eph receptors, are cell-surface proteins that fall into two categories, ephrin-A and ephrin-B, based on their structure and function. EFNB1 proteins are transmembrane and have conserved cytoplasmic tyrosine residues that are phosphorylated upon interaction with an EphB receptor. Also, EFNB1 transduces outside-in signals through C-terminal protein interactions that effect integrin-mediated cell attachment and migration.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 5% glycerol
• Molecular Weight: 25.3 kDa (231aa)
• Purity: > 95% by SDS - PAGE
• Concentration: 1 mg/ml (determined by Bradford assay)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MLAKNLEPVS WSSLNPKFLS GKGLVIYPKI GDKLDIICPR AEAGRPYEYY KLYLVRPEQA AACSTVLDPN VLVTCNRPEQ EIRFTIKFQE FSPNYMGLEF KKHHDYYITS TSNGSLEGLE NREGGVCRTR TMKIIMKVGQ DPNAVTPEQL TTSRPSKEAD NTVKMATQAP GSRGSLGDSD GKHETVNQEE KSGPGASGGS SGDPDGFFNS K
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Pathways: Axon guidance

Gene Information

• Gene Name: EFNB1 ephrin-B1 [ Homo sapiens ]
• Official Symbol: EFNB1
• Synonyms: EFNB1; ephrin-B1; CFND; CFNS; EFL3; EPLG2; Elk-L; LERK2; EFL-3; MGC8782; LERK-2; OTTHUMP00000023456; ELK ligand; EPH-related receptor tyrosine kinase ligand; craniofrontonasal syndrome (craniofrontonasal dysplasia); ligand of eph-related kinase 2; ELK-L
• Gene ID: 1947
• mRNA Refseq: NM_004429
• Protein Refseq: NP_004420
• MIM: 300035
• UniProt ID: P98172
• Chromosome Location: Xq12
• Function: ephrin receptor binding; protein binding