fcer1a
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  • Official Full Name
  • Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
  • Background
  • Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.
  • Synonyms
  • FCER1A; Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide; FCE1A; high affinity immunoglobulin epsilon receptor subunit alpha; Fc-epsilon RI-alpha; Fc epsilon RI alpha-chain; igE Fc receptor subunit alpha; Fc IgE receptor, alpha polypep
Cat.#:FCER1A-2099HTag:His
Source (Host):YeastSpecies:Human
Product nameRecombinant Human FCER1A Protein (26-205 aa), His-tagged
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Cat.#:FCER1A-2710MTag:His|SUMO
Source (Host):E. coli Cell FreeSpecies:Mouse
Product nameRecombinant Mouse FCER1A Protein (24-250 aa), His-SUMO-tagged
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Cat.#:FCER1A-567HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human FCER1A Protein (Met1-Gln205)
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Cat.#:FCER1A-1209HTag:His|SUMO
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FCER1A Protein, His-SUMO-tagged
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Cat.#:FCER1A-193HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human FCER1A, His-tagged, Biotinylated
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Cat.#:FCER1A-204HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human FCER1A, His-tagged
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Cat.#:FCER1A-237HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human FCER1A
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Cat.#:FCER1A-28166THTag:GST
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human FCER1A, GST-tagged
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Cat.#:FCER1A-311HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide, His-tagged
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Cat.#:FCER1A-338HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human FCER1A protein, His-tagged
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Cat.#:FCER1A-725HTag:His
Source (Host):NSO cellsSpecies:Human
Product nameRecombinant Human FCER1A, His-tagged
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Cat.#:FCER1A-8563HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human FCER1A, His tagged
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Cat.#:Fcer1a-8688MTag:Fc
Source (Host):Human CellsSpecies:Mouse
Product nameRecombinant Mouse Fcer1a, Fc tagged
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Cat.#:FCER1A-2304RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat FCER1A Protein
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Cat.#:FCER1A-1394HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human FCER1A cell lysate
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Cat.#:FCER1A-1389MCLTag:N/A
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse FCER1A cell lysate
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Involved Pathway

FCER1A involved in several pathways and played different roles in them. We selected most pathways FCER1A participated on our site, such as Sphingolipid signaling pathway, Phospholipase D signaling pathway, Fc epsilon RI signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FCER1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Sphingolipid signaling pathway
PLCB1; SGMS2; HRAS; BCL2; RAC2; PPP2R2C; GNA12; CERS4; PDPK1; MAPK3
Phospholipase D signaling pathway
CYTH3; SPHK1; FCER1G; GAB1; DNM3; GRM6; LPAR6; PIK3CA; KRAS; MAP2K1
Fc epsilon RI signaling pathway
GAB2; INPP5D; PIK3R5; MAP2K1; PLA2G4F; GM-CSF; PIK3CA; MAP2K6; VAV2; BTK
Asthma
H2-AB1; CCL11; IL4; HLA-DRB3; CD40LG; HLA-DOB; HLA-DRB4; HLA-DMA; HLA-DRB5; HLA-DQA2

Protein Function

FCER1A has several biochemical functions, for example, IgE binding, IgE receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FCER1A itself. We selected most functions FCER1A had, and list some proteins which have the same functions with FCER1A. You can find most of the proteins on our site.
Function
Related Protein
Function IgE binding
Related Protein LGALS3; MS4A2; CD247L; FCER1A; FCER1G; Fcer2a; FCER2
Function IgE receptor activity
Related Protein FCER1A; MS4A2; CD247L; FCER1G

Interacting Protein

FCER1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FCER1A here. Most of them are supplied by our site. Hope this information will be useful for your research of FCER1A.
PDHB