il2rg
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  • Official Full Name
  • interleukin 2 receptor, gamma chain
  • Background
  • CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, also known as common gamma chain (gammac), or IL-2 receptor gamma subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an ess
  • Synonyms
  • IL2RG; interleukin 2 receptor, gamma chain; cytokine receptor common subunit gamma; p64; IL-2RG; gammaC; gamma C receptor; common gamma chain; IL-2R subunit gamma; IL-2 receptor subunit gamma; common cytokine receptor gamma chain; interleukin-2 receptor subunit gamma; gc; [g]c; CD132; gamma(c)
Cat.#:IL2RG-5193HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human IL2RG Protein, GST-tagged
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Cat.#:IL2RG-5194HTag:
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human IL2RG Protein
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Cat.#:IL2RG-14197HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IL2RG, GST-tagged
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Cat.#:IL2RG-29663THTag:Fc
Source (Host):Species:Human
Product nameRecombinant Human IL2RG, Fc-tagged
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Cat.#:IL2RG-49HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human IL2RG, His-tagged
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Cat.#:IL2RG-6963HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human IL2RG, His tagged
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Cat.#:IL2RG-7066HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IL2RG protein, His-tagged
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Cat.#:IL2RG-7289HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human IL2RG, Fc tagged
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Cat.#:IL2RG-949HTag:GST/His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IL2RG Protein, GST-His-tagged
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Cat.#:Il2rg-4005MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Il2rg, His tagged
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Cat.#:Il2rg-7067MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Il2rg protein, His-tagged
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Cat.#:Il2rg-784MTag:FC/His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Il2rg, Fc-His tagged
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Cat.#:Il2rg-7456RTag:Fc
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Il2rg, Fc tagged
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Cat.#:Il2rg-7457RTag:His
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Il2rg, His tagged
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Cat.#:IL2RG-1562RTag:
Source (Host):HEK293Species:Rhesus monkey
Product nameRecombinant Rhesus Monkey IL2RG Protein
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Cat.#:IL2RG-1563RTag:hIgG1
Source (Host):HEK293Species:Rhesus monkey
Product nameRecombinant Rhesus Monkey IL2RG Protein, hIgG1-tagged
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Cat.#:IL2RG-1564RTag:hIgG4
Source (Host):HEK293Species:Rhesus monkey
Product nameRecombinant Rhesus Monkey IL2RG Protein, hIgG4-tagged
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Cat.#:IL2RG-2249RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey IL2RG Protein, His-tagged
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Cat.#:IL2RG-6096CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken IL2RG
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Cat.#:IL2RG-119HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human IL2RG, Gamma, Fc Chimera
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Cat.#:Il2rg-1716MTag:N/A
Source (Host):Baculovirus-Insect CellsSpecies:Mouse
Product nameRecombinant Mouse Interleukin 2 Receptor, Gamma Chain
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Cat.#:IL2RG-1481HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human IL2RG cell lysate
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Cat.#:IL2RG-502HCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human IL2RG cell lysate
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Cat.#:IL2RG-2908MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse IL2RG cell lysate
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Cat.#:IL2RG-1476RCLTag:
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat IL2RG cell lysate
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Involved Pathway

Il2rg involved in several pathways and played different roles in them. We selected most pathways Il2rg participated on our site, such as Cytokine-cytokine receptor interaction, Endocytosis, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Il2rg were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine-cytokine receptor interaction
CCR6A; Ccl12; CCL4L1; IL25; GM10591; PDGFAB; IFNA6; TNFRSF19; TGFB1A; CD70
Endocytosis
HRASB; SRC; RAB31; MDM2; GRK7A; CHMP4C; CAPZA1A; SNX4; STAMBPB; ASAP3
PIK-Akt signaling pathway
GH2; VEGFA; Kitl; GNB4; PDGFRB; IL6R; RBL2; CCND2; PKN3; FGF5
Jak-STAT signaling pathway
CNTFR; SOCS6B; STAT1; MPL; IL24; STAT1A; IL6R; IL6; CCND2A; LEPA
Measles
TNFRSF10A; PIK3CD; Ifna11; HSPA1L; OAS3; STAT2; CD209; CD209C; STAT5A; IL2RB
HTLV-I infection
VDAC2; NFATC2; GPS2; POLE; XIAP; ZFP36; HLA-DRB1; PIK3CD; PIK3CA; POLD4
Inflammatory bowel disease (IBD)
H2-AB1; NFKB1; IL23R; TLR5; STAT3; IL23; IL17A; IL1B; IL22; NFATC1
Primary i
CD4; BTK; RAG1; IGLL1; LCK; RFX5; IL2RG; DCLRE1C; TNFRSF13B; TAP2
nodeficiency
RAG2; CD4; RFXAP; ORAI1; AICDA; RFXANK; CD79A; DCLRE1C; AIRE; IKBKG

Protein Function

Il2rg has several biochemical functions, for example, interleukin-2 binding, contributes_to interleukin-2 receptor activity, contributes_to interleukin-4 receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Il2rg itself. We selected most functions Il2rg had, and list some proteins which have the same functions with Il2rg. You can find most of the proteins on our site.
Function
Related Protein
Function interleukin-2 binding
Related Protein IL2RB; IL2RG; IL2RA
Function contributes_to interleukin-2 receptor activity
Related Protein IL2RG; IL2RB
Function contributes_to interleukin-4 receptor activity
Related Protein IL2RG
Function interleukin-7 binding
Related Protein IL2RG
Function contributes_to interleukin-7 receptor activity
Related Protein IL2RG
Function protein binding
Related Protein VASNA; C15orf57; SYT4; RC3H2; UBOX5; TGIF2LY; ABCB9; ARHGEF1; TUBA1C; DHX38

Interacting Protein

Il2rg has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Il2rg here. Most of them are supplied by our site. Hope this information will be useful for your research of Il2rg.
IL4; IL4R; NOTCH2NL; IL15RA; IL7; IL7R; GRB2

Il2rg Related Articles

Motobayashi, M; Inaba, Y; et al. Successful treatment for West syndrome with severe combined immunodeficiency. BRAIN & DEVELOPMENT 37:140-144(2015).
Wan, SS; Zhao, ED; et al. Tumor-Associated Macrophages Produce Interleukin 6 and Signal via STAT3 to Promote Expansion of Human Hepatocellular Carcinoma Stem Cells. GASTROENTEROLOGY 147:1393-1404(2014).

Il2rg Related Gene Family

IL