sdc1
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  • Official Full Name
  • syndecan 1
  • Background
  • CD138/Syndecan-1 is a transmembrane heparin sulphate proteoglycan which is made up of one core protein and five glycosaminoglycan. CD138 is expected to play a role in cell adhesion. It is expressed on the surface of pre-B cells and plasma cells but is absent from mature B cells. It is lost from the apoptotic myeloma cells.
  • Synonyms
  • SDC1; syndecan 1; syndecan-1; synstatin; Sstn; Synd; CD138; Synd1; syn-1; AA408134; AA409076
Cat.#:SDC1-327HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human SDC1 Protein (Gln 23 - Gly 254), His-tagged
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Cat.#:Sdc1-8784RATag:Fc
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Sdc1 protein, Fc-tagged, APC labeled
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Cat.#:Sdc1-8784RPTag:Fc
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Sdc1 protein, Fc-tagged, R-PE labeled
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Cat.#:SDC1-15HTag:His
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human SDC1 Protein, His-tagged
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Cat.#:SDC1-188HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human SDC1 Protein, His-tagged
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Cat.#:SDC1-2033HTag:His|GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SDC1 protein, His & GST-tagged
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Cat.#:SDC1-29HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SDC1 Protein, His-tagged
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Cat.#:SDC1-31494THTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SDC1
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Cat.#:SDC1-3352HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human SDC1, His tagged
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Cat.#:SDC1-523HTag:His
Source (Host):NSO CellsSpecies:Human
Product nameRecombinant Human SDC1 Protein, His-tagged
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Cat.#:Sdc1-2034MTag:His|GST
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Sdc1 protein, His & GST-tagged
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Cat.#:Sdc1-4065MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Sdc1, His tagged
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Cat.#:Sdc1-2035RTag:His|GST
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Sdc1 protein, His & GST-tagged
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Cat.#:SDC1-5284RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat SDC1 Protein
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Cat.#:Sdc1-8784RTag:Fc
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Sdc1, Fc tagged
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Cat.#:Sdc1-8785RTag:His
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Sdc1, His tagged
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Cat.#:SDC1-2032CTag:His|T7
Source (Host):E. coliSpecies:Cattle
Product nameRecombinant Cattle SDC1 protein, His & T7-tagged
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Cat.#:SDC1-2390HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Syndecan 1
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Cat.#:SDC1-2253HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human SDC1 cell lysate
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Cat.#:SDC1-2089MCLTag:N/A
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse SDC1 cell lysate
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Cat.#:SDC1-1295RCLTag:N/A
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat SDC1 cell lysate
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Involved Pathway

SDC1 involved in several pathways and played different roles in them. We selected most pathways SDC1 participated on our site, such as ECM-receptor interaction, Cell adhesion molecules (CAMs), Malaria, which may be useful for your reference. Also, other proteins which involved in the same pathway with SDC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
ECM-receptor interaction
ITGA6B; COL6A4; Reln; ITGB1B.2; ITGB3B; COL6A5; ITGA3; SV2B; LAMC3; COL24A1
Cell adhesion molecules (CAMs)
ITGB1B.2; CDH5; CD99; CADM3; NLGN3; HLA-DMA; NLGN2; MHC1UXA2; CD276; Siglec1
Malaria
HBB-B2; VCAM1; CCL2; ITGB2L; LRP1; THBS3; GYPC; PECAM1; TLR4; MET
Proteoglycans in cancer
RAF1; WNT3A; WNT8A; PIK3CB; ERBB4; ITGAV; IGF1; PIK3R1; MAPK1; BRAF

Protein Function

SDC1 has several biochemical functions, for example, glycoprotein binding, protein C-terminus binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SDC1 itself. We selected most functions SDC1 had, and list some proteins which have the same functions with SDC1. You can find most of the proteins on our site.
Function
Related Protein
Function glycoprotein binding
Related Protein FBXO27; SDCBP; SDC1; STX1A; F7; PIP; FYN; FOXRED2; SERPINA1E; FGFR1
Function protein C-terminus binding
Related Protein SIRT1; XRCC5; KSR1; TOP2A; ITPR1; CORO1A; NEIL1; PRDX3; CD2AP; JAK2
Function protein binding
Related Protein NUDT10; ADAP1; TEK; PTPRS; EFNB1; WIPI2; STX6; ZNF207; KIF5A; CDC42

Interacting Protein

SDC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SDC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SDC1.
PECAM1; q7ci82_yerpe; MNDA; PYHIN1; PDCD6IP

SDC1 Related Articles

Wang, HY; Jin, HN; et al. Cytoplasmic Domain Interactions of Syndecan-1 and Syndecan-4 with alpha 6 beta 4 Integrin Mediate Human Epidermal Growth Factor Receptor (HER1 and HER2)-dependent Motility and Survival. JOURNAL OF BIOLOGICAL CHEMISTRY 289:30318-30332(2014).
Gonzales, JC; Gordts, PLSM; et al. Apolipoproteins E and AV mediate lipoprotein clearance by hepatic proteoglycans. JOURNAL OF CLINICAL INVESTIGATION 123:2742-2751(2013).