SDC1
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Official Full Name
syndecan 1
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Overview
CD138/Syndecan-1 is a transmembrane heparin sulphate proteoglycan which is made up of one core protein and five glycosaminoglycan. CD138 is expected to play a role in cell adhesion. It is expressed on the surface of pre-B cells and plasma cells but is absent from mature B cells. It is lost from the apoptotic myeloma cells. -
Synonyms
SDC1; syndecan 1; syndecan-1; synstatin; Sstn; Synd; CD138; Synd1; syn-1; AA408134; AA409076;
- Recombinant Proteins
- Cell & Tissue Lysates
- GMP Proteins
- Protein Pre-coupled Magnetic Beads
- Cattle
- Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
- Cynomolgus
- Homo sapiens (Human)
- Human
- Mesocricetus auratus (Golden hamster)
- Mouse
- Mus musculus (Mouse)
- Rat
- E.coli
- E.coli expression system
- HEK293
- HEK293F
- Human Cell
- Human Cells
- Mammalian Cell
- Mammalian cells
- Mammalian Cells
- Yeast
- C
- hFc
- 6×His
- His
- Fc
- Avi
- His (Fc)
- GST
- His|GST
- His|T7
- SUMO
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- SDC1 Related Articles
- SDC1 Related Research Area
SDC1 involved in several pathways and played different roles in them. We selected most pathways SDC1 participated on our site, such as ECM-receptor interaction, Cell adhesion molecules (CAMs), Malaria, which may be useful for your reference. Also, other proteins which involved in the same pathway with SDC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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ECM-receptor interaction | LAMA3;ITGAV;COL1A1;ITGB3;Reln;LAMA2;ITGB1;ITGB7;COL2A1A |
Cell adhesion molecules (CAMs) | BMA1;NADL1.2;ITGB2L;HLA-DMA;PVRL3B;OCLN;CLDN22;PTPRC;PVR |
Malaria | TLR2;KLRB1;DARC;THBS3;HBB-B2;HGF;GYPC;KLRC4-KLRK1;IL1B |
Proteoglycans in cancer | ACTB;ITPR1;PPP1CC;IGF1R;SDC1;ANK1;ARAF;CCND1;PLAU |
SDC1 has several biochemical functions, for example, glycoprotein binding, protein C-terminus binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SDC1 itself. We selected most functions SDC1 had, and list some proteins which have the same functions with SDC1. You can find most of the proteins on our site.
Function | Related Protein |
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glycoprotein binding | SELP;BBC3;TGFB1;DNAJA2;AZGP1;DNAJC5;ITGB2;VIM;CNTN1 |
protein C-terminus binding | ERCC2;PQBP1;PABPC1;PIAS4;BCL10;CDK7;SP1;PEX16;MAP2K1 |
protein binding | C15orf23;JAM2A;REST;RAB9B;LRRFIP1;TSSK3;JAK3;DCPS;ASCC1 |
SDC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SDC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SDC1.
PECAM1; q7ci82_yerpe; MNDA; PYHIN1; PDCD6IP
- Q&As
- Reviews
Q&As (7)
Ask a questionSDC1 is predominantly expressed in epithelial tissues.
The ZEB1 transcription factor acts on SDC1 and represses its expression.
SDC1 protein expression was positively correlated with E-cadherin protein expression and acted synergistically.
Inhibition of SDC1 expression promotes tumor growth, invasion and metastasis.
SDC1 is involved in the study of diseases such as liver cancer, colon cancer and breast cancer.
SDC1 is localized to the cell membrane.
SDC1 is involved in biological processes such as cell proliferation, differentiation, and adhesion.
Customer Reviews (3)
Write a reviewEach customer has a dedicated customer service to provide one-on-one, specialized service that solved the problem in my experiment.
High quality product at a good price, a satisfactory shopping experience.
The product brochure is very detailed and has comprehensive basic information about the SDC1 protein.
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