Recombinant Human SDC1
Cat.No. : | SDC1-31494TH |
Product Overview : | Recombinant fragment, corresponding to amino acids 18-218 of Human Syndecan with proprietary tag, 48kDa. |
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Description : | The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. |
Source : | E. coli |
Form : | Liquid |
Storage buffer : | Preservative: NoneConstituents: 20% Glycerol, 50mM Tris acetate, 1mM EDTA, pH 7.5BSA and Azide free |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
Sequence Similarities : | Belongs to the syndecan proteoglycan family. |
Tag : | Non |
Gene Name : | SDC1 syndecan 1 [ Homo sapiens ] |
Official Symbol : | SDC1 |
Synonyms : | SDC1; syndecan 1; SDC; syndecan-1; CD138; SYND1; syndecan; syndecan proteoglycan 1; |
Gene ID : | 6382 |
mRNA Refseq : | NM_001006946 |
Protein Refseq : | NP_001006947 |
MIM : | 186355 |
Uniprot ID : | P18827 |
Chromosome Location : | 2p24.1 |
Pathway : | Arf6 trafficking events, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Chylomicron-mediated lipid transport, organism-specific biosystem; ECM-receptor interaction, organism-specific biosystem; |
Function : | cytoskeletal protein binding; glycoprotein binding; lipoprotein lipase activity; protein C-terminus binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
SDC1-126H | Recombinant Human SDC1 Protein, C-His-tagged | +Inquiry |
Sdc1-2047R | Recombinant Rat Sdc1 Protein, His-tagged | +Inquiry |
SDC1-1715R | Recombinant Rabbit SDC1 protein, His-tagged | +Inquiry |
Sdc1-7958M | Recombinant Mouse Sdc1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Sdc1-8784R | Recombinant Rat Sdc1 protein(Met1-Lys253), hFc-tagged | +Inquiry |
◆ Lysates | ||
SDC1-2089MCL | Recombinant Mouse SDC1 cell lysate | +Inquiry |
SDC1-1295RCL | Recombinant Rat SDC1 cell lysate | +Inquiry |
SDC1-2253HCL | Recombinant Human SDC1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewEach customer has a dedicated customer service to provide one-on-one, specialized service that solved the problem in my experiment.
High quality product at a good price, a satisfactory shopping experience.
The product brochure is very detailed and has comprehensive basic information about the SDC1 protein.
Q&As (7)
Ask a questionSDC1 is predominantly expressed in epithelial tissues.
The ZEB1 transcription factor acts on SDC1 and represses its expression.
SDC1 protein expression was positively correlated with E-cadherin protein expression and acted synergistically.
Inhibition of SDC1 expression promotes tumor growth, invasion and metastasis.
SDC1 is involved in the study of diseases such as liver cancer, colon cancer and breast cancer.
SDC1 is localized to the cell membrane.
SDC1 is involved in biological processes such as cell proliferation, differentiation, and adhesion.
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