Recombinant Human Syndecan 1

• Cat.No.: SDC1-2390H
• Product Overview: Recombinant Human Syndecan 1encoding 18-218 aa expressed inE.coli.

Specification

• Cat. No.: SDC1-2390H
• Description: CD138 / Syndecan-1 is a transmembrane heparin sulphate proteoglycan which is made up of one core protein and five glycosaminoglycan. CD138 is expected to play a role in cell adhesion. It is expressed on the surface of pre-B cells and plasma cells but is absent from mature B cells. It is a selective marker for B cell lymphoblastic leukemia and lymphoplasmocytoid leukemia. It is lost from the apoptotic myeloma cells; hence is a useful marker for viable myeloma cells.
• Source: E. coli.
• Presentation: 100μl purified human CD138 protein at 100μg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA, 20% Glycerol without BSA and Sodium Azide.
• Application: ELISA, Inhibition Assays, Western Blotting.
• Characterization: On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 48kDa including GST.
• Storage: Store vial at -20℃ to -80℃. When stored at the recommended temperature, this protein is stable for 12 months.
• Tag: Non
• Protein length: 18-218

Gene Information

• Gene Name: SDC1 syndecan 1 [ Homo sapiens ]
• Synonyms: SDC1; syndecan 1; SDC; CD138; SYND1; syndecan; syndecan-1; CD138 antigen; syndecan proteoglycan 1; heparan sulfate proteoglycan fibroblast growth factor receptor
• Gene ID: 6382
• mRNA Refseq: NM_001006946
• Protein Refseq: NP_001006947
• MIM: 186355
• UniProt ID: P18827
• Chromosome Location: 2p24.1
• Pathway: Cell adhesion molecules (CAMs); ECM-receptor interaction; Metabolism of lipids and lipoproteins
• Function: cytoskeletal protein binding; protein C-terminus binding

Reviews

10/14/2023

Each customer has a dedicated customer service to provide one-on-one, specialized service that solved the problem in my experiment.

07/22/2023

High quality product at a good price, a satisfactory shopping experience.

07/13/2023

The product brochure is very detailed and has comprehensive basic information about the SDC1 protein.

Q&As

In which tissues is SDC1 mainly expressed?

SDC1 is predominantly expressed in epithelial tissues.

How is SDC1 linked to the ZEB1 transcription factor?

The ZEB1 transcription factor acts on SDC1 and represses its expression.

How does SDC1 relate to the expression of the tight junction protein E-cadherin?

SDC1 protein expression was positively correlated with E-cadherin protein expression and acted synergistically.

What are the effects of inhibiting SDC1 expression?

Inhibition of SDC1 expression promotes tumor growth, invasion and metastasis.

What diseases is SDC1 involved in?

SDC1 is involved in the study of diseases such as liver cancer, colon cancer and breast cancer.

Where is SDC1 located?

SDC1 is localized to the cell membrane.

What biological processes is SDC1 involved in?

SDC1 is involved in biological processes such as cell proliferation, differentiation, and adhesion.