Recombinant Rat Sdc1 protein(Met1-Lys253), hFc-tagged

• Cat.No.: Sdc1-8784R
• Product Overview: Recombinant Rat SDC1 (P26260) (Met1-Lys253) was expressed in HEK293, fused with the Fc region of Human IgG1 at the C-terminus.

Specification

• Source: HEK293
• Species: Rat
• Tag: Fc
• Protein length: Met1-Lys253
• Form: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
• Molecular Mass: The recombinant Rat SDC1/Fc is a disulfide-linked homodimer. The reduced monomer comprises 472 amino acids and has a predicted molecular mass of 51.2 kDa. The apparent molecular mass of the protein is approximately 92 kDa in SDS-PAGE under reducing conditions.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: > 90 % as determined by SDS-PAGE
• Storage: Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: Sdc1 syndecan 1 [ Rattus norvegicus ]
• Official Symbol: Sdc1
• Synonyms: SDC1; syndecan 1; syndecan-1; HSPG; Synd1; SYNDECA; Syndecan
• Gene ID: 25216
• mRNA Refseq: NM_013026
• Protein Refseq: NP_037158

Reviews

10/14/2023

Each customer has a dedicated customer service to provide one-on-one, specialized service that solved the problem in my experiment.

07/22/2023

High quality product at a good price, a satisfactory shopping experience.

07/13/2023

The product brochure is very detailed and has comprehensive basic information about the SDC1 protein.

Q&As

In which tissues is SDC1 mainly expressed?

SDC1 is predominantly expressed in epithelial tissues.

How is SDC1 linked to the ZEB1 transcription factor?

The ZEB1 transcription factor acts on SDC1 and represses its expression.

How does SDC1 relate to the expression of the tight junction protein E-cadherin?

SDC1 protein expression was positively correlated with E-cadherin protein expression and acted synergistically.

What are the effects of inhibiting SDC1 expression?

Inhibition of SDC1 expression promotes tumor growth, invasion and metastasis.

What diseases is SDC1 involved in?

SDC1 is involved in the study of diseases such as liver cancer, colon cancer and breast cancer.

Where is SDC1 located?

SDC1 is localized to the cell membrane.

What biological processes is SDC1 involved in?

SDC1 is involved in biological processes such as cell proliferation, differentiation, and adhesion.