Active GMP Recombinant Human SDC1 protein, Fc-tagged

• Cat.No.: SDC1-187HG
• Product Overview: GMP Recombinant Human SDC1 protein(NP_001006947)(463 aa), fused with Fc Tag at the C-terminal, was expressed in HEK293 cell in an animal component free process under cGMP guidelines.

Specification

• Source: HEK293
• Species: Human
• Tag: Fc
• Form: Freeze-dried powder contains Sterile PBS (pH 7.4) with 6% mannitol.
• Bio-activity: Use immobilized protein to enhance the ability of Saos2 (human osteosarcoma cells) to adhere to human fibronectin. Add 5×104 cells/well to human Syndocan-1 and human fibronectin (0.5ug/ml) coated plates , Cell adhesion was enhanced in a dose-dependent manner. The ED 50 for this effect is 5-10ug/ml.
• Molecular Mass: Recombinant Human SDC1 protein contains 463 aa. It has a predicted MW of 50.8 kDa.
• Protein length: DNA sequence encoding Human CD138(UniProtKB/Swiss-Prot: P18827.3) was expressed with Fc tag at the C-terminal.
• Endotoxin: <0.1EU/ug
• Purity: >=95% by SDS-PAGE and HPLC
• Storage: The lyophilized preparation can be stored at 4°C for 24 months, and the dissolved liquid can be stored at -20°C for 6-12 months to avoid repeated freezing and thawing
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: SDC1 syndecan 1 [ Homo sapiens ]
• Official Symbol: SDC1
• Synonyms: SDC1; Syndecan-1; SYND1; SDC
• Gene ID: 6382
• mRNA Refseq: NM_001006946
• Protein Refseq: NP_001006947
• MIM: 186355
• UniProt ID: P18827

Reviews

10/14/2023

Each customer has a dedicated customer service to provide one-on-one, specialized service that solved the problem in my experiment.

07/22/2023

High quality product at a good price, a satisfactory shopping experience.

07/13/2023

The product brochure is very detailed and has comprehensive basic information about the SDC1 protein.

Q&As

In which tissues is SDC1 mainly expressed?

SDC1 is predominantly expressed in epithelial tissues.

How is SDC1 linked to the ZEB1 transcription factor?

The ZEB1 transcription factor acts on SDC1 and represses its expression.

How does SDC1 relate to the expression of the tight junction protein E-cadherin?

SDC1 protein expression was positively correlated with E-cadherin protein expression and acted synergistically.

What are the effects of inhibiting SDC1 expression?

Inhibition of SDC1 expression promotes tumor growth, invasion and metastasis.

What diseases is SDC1 involved in?

SDC1 is involved in the study of diseases such as liver cancer, colon cancer and breast cancer.

Where is SDC1 located?

SDC1 is localized to the cell membrane.

What biological processes is SDC1 involved in?

SDC1 is involved in biological processes such as cell proliferation, differentiation, and adhesion.