| Description : |
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
His |
| Form : |
Lyophilized from a 0.2 µM filtered solution of 20mM PB, 150mM NaCl, pH7.4 |
| Molecular Mass : |
20.39kD |
| AA Sequence : |
QIVATNLPPEDQDGSGDDSDNFSGS GAGALQDITLSQQTPSTWKDTQLLT AIPTSPEPTGLEATAASTSTLPAGE GPKEGEAVVLPEVEPGLTAREQEAT PRPRETTQLPTTHQASTTTATTAQE PATSHPHRDMQPGHHETSTPAGPSQ ADLHTPHTEDGGPSATERAAEDGAS SQLPAAEGSGEQDFTFETSGENTAV VAVEPDRRNQSPVDQGATGASQGLL DRKEVDHHHHHH |
| Endotoxin : |
Endotoxin level is <0.1 ng/µg of protein (<1EU/µg). |
| Purity : |
>95% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration : |
Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
