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Official Full Name CD3g molecule, gamma (CD3-TCR complex)
Background The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency.
Synonyms CD3G; CD3g molecule, gamma (CD3-TCR complex); CD3g antigen, gamma polypeptide (TiT3 complex); T-cell surface glycoprotein CD3 gamma chain; T-cell receptor T3 gamma chain; CD3g molecule, epsilon (CD3-TCR complex); T-cell antigen receptor complex, gamma sub
    • Species :
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Mammalian Cell
    • Wheat Germ
    • Yeast
    • Tag :
    • Fc
    • GST
    • His
    • Flag
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CD3E & CD3G-146H Recombinant Human CD3E & CD3G protein, Fc-tagged HEK293 Fc
    Human CD3E & CD3G-251H Recombinant Human CD3E & CD3G protein, His/Fc-tagged HEK293 His/Fc
    Human CD3E & CD3G-342H Recombinant Human CD3E & CD3G protein, His & Fc & Flag-tagged HEK293 His/Fc/Flag
    Human CD3E & CD3G-761HCL Recombinant Human CD3E & CD3G cell lysate Human Cell N/A
    Human CD3G-0805H Recombinant Human CD3G Protein, GST-Tagged Wheat Germ GST
    Human CD3G-26368TH Recombinant Human CD3G Wheat Germ N/A
    Human CD3G-370H Recombinant Human CD3G Mammalian Cell His
    Human CD3G-4903H Recombinant Human CD3G protein, Fc-tagged HEK293 Fc
    Human CD3G-7556H Recombinant Human CD3G, His-tagged E.coli His
    Human CD3G-7675HCL Recombinant Human CD3G 293 Cell Lysate HEK293 N/A
    Mouse CD3G-3088M Recombinant Mouse CD3G Protein Mammalian Cell His
    Mouse Cd3g-323M Recombinant Mouse CD3G Protein, Fc-tagged HEK293 Fc
    Mouse Cd3g-324M Recombinant Mouse CD3G Protein HEK293 N/A
    Rat CD3G-1251R Recombinant Rat CD3G Protein Mammalian Cell His
    Cynomolgus Monkey CD3G-2104C Recombinant Cynomolgus Monkey CD3G Protein (23-113 aa), His-tagged Yeast His
    Cynomolgus Monkey CD3G-391C Recombinant Cynomolgus CD3G Protein, His-tagged Mammalian Cell His
    Rhesus Macaque CD3G-738R Recombinant Rhesus monkey CD3G Protein, His-tagged Mammalian Cell His

    cd3g involved in several pathways and played different roles in them. We selected most pathways cd3g participated on our site, such as Hematopoietic cell lineage, T cell receptor signaling pathway, Chagas disease (American trypanosomiasis), which may be useful for your reference. Also, other proteins which involved in the same pathway with cd3g were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Hematopoietic cell lineage ITGA6; IL4R; KIT; ITGA5; IL11RA; CD59A; Kitl; GP1BA; EPOR; IL6R
    T cell receptor signaling pathway CD3E; IKBKG; RAF1; IL4; PPP3CA; ZAP70; SHB; GRB2; SLA1; CD28
    Chagas disease (American trypanosomiasis) PPP2CB; PLCB2; TNFRSF1A; GNA11; CXCL8; TLR9; ACE; CFLAR; CCL3L3; CD247
    Measles PIK3R2; TBK1; CCND1; IL12B; EIF2AK2; TLR7; CCNE1; Il2; FAS; STAT1
    HTLV-I infection KAT2A; LTA; DVL1; XIAP; BCL2L1; SLC25A6; CD40; MAP3K14; DLG1; TGFB2

    cd3g has several biochemical functions, for example, T cell receptor binding, protein heterodimerization activity, receptor signaling complex scaffold activity. Some of the functions are cooperated with other proteins, some of the functions could acted by cd3g itself. We selected most functions cd3g had, and list some proteins which have the same functions with cd3g. You can find most of the proteins on our site.

    Function Related Protein
    T cell receptor binding HLA-A; FYN; EPS8L1; H2-Q10; CD3G; CD3E; CD1d1; DOCK2
    protein heterodimerization activity ATF6; HIST2H2L; Bcl2a1b; RRAGA; TENM3; SIM1; IKBKG; HIST1H2B8; USF2; SRI
    receptor signaling complex scaffold activity CD3E; SPAG9A; LDLRAP1; MMS19; G3BP2; GRIP2A; MAGI2; AXIN1; GRIP1; NCK1
    transmembrane signaling receptor activity KIR2DS2; TLR4; HIST2H3C2; CELSR1; OR4C13; NRXN2; EDAR; GHRHR2; NCR2; GHRHRL

    cd3g has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cd3g here. Most of them are supplied by our site. Hope this information will be useful for your research of cd3g.


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