CD3G

  • Official Full Name

    CD3g molecule, gamma (CD3-TCR complex)

  • Overview

    The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency.
  • Synonyms

    CD3G; CD3g molecule, gamma (CD3-TCR complex); CD3g antigen, gamma polypeptide (TiT3 complex); T-cell surface glycoprotein CD3 gamma chain; T-cell receptor T3 gamma chain; CD3g molecule, epsilon (CD3-TCR complex); T-cell antigen receptor complex, gamma sub;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus Monkey
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rhesus Macaque
  • E.coli
  • E.coli expression system
  • HEK293
  • Human Cell
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Yeast
  • C
  • His
  • Fc
  • Flag
  • mFc
  • GST
  • His (Fc)
  • Avi
  • His|Fc|Flag
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CD3E & CD3G-342H Active Recombinant Human CD3E & CD3G protein, His & Fc & Flag-tagged HEK293 His/Fc/Flag
Human CD3E & CD3G-251H Active Recombinant Human CD3E & CD3G protein, Flag & mFc-tagged HEK293 Flag & mFc
Human CD3G-0805H Recombinant Human CD3G Protein, GST-Tagged Wheat Germ GST
Human CD3G-26368TH Recombinant Human CD3G Wheat Germ N/A
Human CD3G-370H Recombinant Human CD3G Mammalian Cell His
Human CD3G-7556H Recombinant Human CD3G, His-tagged E.coli His
Human CD3G-4903H Recombinant Human CD3G protein, Fc-tagged HEK293 Fc
Human CD3E & CD3G-761HCL Recombinant Human CD3E & CD3G cell lysate Human Cell N/A
Human CD3G-7675HCL Recombinant Human CD3G 293 Cell Lysate HEK293 N/A
Human CD3G-678H Recombinant Human CD3G Protein, His-tagged E.coli N-His
Human CD3E & CD3G-146H Recombinant Human CD3E & CD3G protein, Fc-tagged HEK293 Fc
Human CD3G-170H Recombinant Human CD3G Protein, C-His-tagged E.coli C-His
Human CD3G-5286H Recombinant Human CD3G Protein (Met1-Ser116), C-His tagged Mammalian cells C-His
Human CD3G-1011H Recombinant Human CD3G protein, Fc-tagged HEK293 Fc
Human CD3G-2633H Recombinant Human CD3G Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human CD3G-2633H-B Recombinant Human CD3G Protein Pre-coupled Magnetic Beads HEK293
Mouse CD3G-3088M Recombinant Mouse CD3G Protein Mammalian Cell His
Mouse Cd3g-324M Recombinant Mouse CD3G Protein HEK293 N/A
Mouse CD3G-1461M Recombinant Mouse CD3G Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse CD3G-1461M-B Recombinant Mouse CD3G Protein Pre-coupled Magnetic Beads HEK293
Mouse Cd3g-323M Recombinant Mouse CD3G Protein, Fc-tagged HEK293 Fc
Rat CD3G-1251R Recombinant Rat CD3G Protein Mammalian Cell His
Rat CD3G-909R-B Recombinant Rat CD3G Protein Pre-coupled Magnetic Beads HEK293
Rat CD3G-909R Recombinant Rat CD3G Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey CD3G-391C Recombinant Cynomolgus CD3G Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey CD3G-2104C Recombinant Cynomolgus Monkey CD3G Protein (23-113 aa), His-tagged Yeast His
Cynomolgus Monkey CD3G-139C-B Recombinant Cynomolgus Monkey CD3G Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey CD3G-139C Recombinant Cynomolgus Monkey CD3G Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Homo sapiens (Human) RFL19012HF Recombinant Full Length Human T-Cell Surface Glycoprotein Cd3 Gamma Chain(Cd3G) Protein, His-Tagged E.coli expression system His
Mus musculus (Mouse) RFL22457MF Recombinant Full Length Mouse T-Cell Surface Glycoprotein Cd3 Gamma Chain(Cd3G) Protein, His-Tagged E.coli expression system His
Rhesus Macaque CD3G-738R Recombinant Rhesus monkey CD3G Protein, His-tagged Mammalian Cell His
Rhesus Macaque CD3G-564R-B Recombinant Rhesus Macaque CD3G Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CD3G-564R Recombinant Rhesus Macaque CD3G Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CD3G Related Research Area

CD3G involved in several pathways and played different roles in them. We selected most pathways CD3G participated on our site, such as Hematopoietic cell lineage, T cell receptor signaling pathway, Chagas disease (American trypanosomiasis), which may be useful for your reference. Also, other proteins which involved in the same pathway with CD3G were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Hematopoietic cell lineageIl6ra;TFRC;CD59;CD8B;GP1BA;KITLG;GP1BB;FCGR1A;FLT3
T cell receptor signaling pathwayFYN;NRAS;CD28;NFATC3;PLCG1;NCK2;PIK3R1;PIK3CD;NFATC2
Chagas disease (American trypanosomiasis)TLR6;CCL3L3;CFLAR;TLR9;GNA11;PLCB3;GNAI3;NFKB1;IFNG
MeaslesIL12B;TLR2;IL4;CCND1;CCNE2;TNFSF10;IL2RA;NFKB1;SH2D1A
HTLV-I infectionWNT6;DVL1;HLA-DOA;FZD1;WNT3A;TGFB2;POLE2;VDAC2;CDC27

CD3G has several biochemical functions, for example, T cell receptor binding, protein heterodimerization activity, receptor signaling complex scaffold activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CD3G itself. We selected most functions CD3G had, and list some proteins which have the same functions with CD3G. You can find most of the proteins on our site.

Function Related Protein
T cell receptor bindingCD3G;FYN;HLA-A;CD1d1;EPS8L1;H2-Q10;CD3E;DOCK2
protein heterodimerization activityIRAK1;HIST2H2AC;IKZF4;CUL3;BOKB;TIMELESS;NPM1;HOMER2;RALGAPA2
receptor signaling complex scaffold activityCD3G;GRIP2A;CARD10;SPAG9;LDLRAP1;SPAG9A;CD3E;G3BP2;MMS19
transmembrane signaling receptor activityEGFR;TLR9;PTH1RB;GLP1R;IL1R1;SIGLEC8;LILRB3;CALCRLA;GPR98

CD3G has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD3G here. Most of them are supplied by our site. Hope this information will be useful for your research of CD3G.

CD3E

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