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Recombinant Human EFNA1 protein, His-tagged

Cat.No. : EFNA1-4190H
Product Overview : Recombinant protein of human ephrin-A1 (EFNA1), transcript variant 2, full length was expressed in E. coli with N-terminal HIS tag.
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Description : Ephrins are a family of molecules which bind to tyrosine kinase receptor Eph. The Eph receptor and their membrane-attached ligands, ephrins, show diverse expression patterns during development. The crucial roles of Eph and ephrins during development suggest involvement of these genes in congenital disorders affecting the nervous system and other tissues. Eph receptors and ephrins may be involved in carcinogenesis.
Source : E. coli
Species : Human
Tag : His
Form : 25mM Tris, pH 8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
Molecular Mass : 19.3 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for at least 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : EFNA1 ephrin-A1 [ Homo sapiens ]
Official Symbol : EFNA1
Synonyms : EFNA1; B61; ECKLG; EFL1; EPLG1; LERK-1; TNFAIP4; Ephrin-A1; OTTHUMP00000033242; OTTHUMP00000033271; EPH-related receptor tyrosine kinase ligand 1; Immediate early response protein B61; Tumor necrosis factor, alpha-induced protein 4; Ligand of eph-related kinase 1
Gene ID : 1942
mRNA Refseq : NM_182685.1
Protein Refseq : NP_872626
MIM : 191164
UniProt ID : P20827

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can EFNA1 be a target for therapeutic interventions in cancer treatment? 05/06/2021

Yes, EFNA1 is being investigated as a potential therapeutic target in cancer treatment, aiming to develop drugs that modulate its activity.

Are there diagnostic applications for EFNA1 in cancer detection? 01/15/2021

Researchers are exploring the use of EFNA1 as a biomarker for cancer detection, with studies suggesting its potential as a diagnostic tool.

How does EFNA1 interact with the Eph receptors, and what is the significance of this interaction? 04/16/2019

EFNA1 binds to Eph receptors, initiating cell signaling pathways that regulate various cellular processes, making this interaction crucial for normal physiological functions.

How does EFNA1 impact cancer research and treatment? 02/02/2018

EFNA1 is implicated in cancer progression, influencing cell migration and invasion. Understanding its role can potentially lead to targeted therapies for certain cancers.

Are there any neurological disorders associated with EFNA1 dysregulation? 10/26/2016

Dysregulation of EFNA1 has been linked to certain neurological disorders, including Alzheimer's disease and neurodevelopmental disorders.

Customer Reviews (3)

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Reviews
08/15/2019

    Their prompt assistance and willingness to go above and beyond to ensure my success have been immensely valuable.

    04/04/2019

      Its purity, stability, and consistency are unparalleled, ensuring reliable and reproducible results in my research.

      11/22/2016

        This protein has proven to be an invaluable asset in my experiments, enabling accurate and precise measurements with exceptional sensitivity.

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