Recombinant Human EFNA1 protein(Met1-Ser182), His-tagged

Cat.No. : EFNA1-2238H
Product Overview : Recombinant Human Ephrin-A1 (NP_004419.2)(Met 1-Ser182) was expressed in HEK293, fused with a polyhistidine tag at the C-terminus.
Availability July 25, 2024
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Source : HEK293
Species : Human
Tag : His
Protein length : Met1-Ser182
Form : Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Bio-activity : Measured by its binding ability in a functional ELISA. Immobilized Human Ephrin-A1 His at 2 μg/ml (100 μl/well) can bind Human EphA1 hFc, the EC50 of Human EphA1 hFc is 8.0-48.0 ng/mL.
Molecular Mass : The recombinant human Ephrin-A1 comprises 175 amino acids a predicted molecular mass of 20.8 kDa. As a result of glycosylation, rh Ephrin-A1 migrates as an approximately 26 kDa band in SDS-PAGE under reducing conditions.
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : > 97 % as determined by SDS-PAGE
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : EFNA1 ephrin-A1 [ Homo sapiens ]
Official Symbol : EFNA1
Synonyms : EFNA1; ephrin-A1; EPLG1, TNFAIP4; ECKLG; LERK1; TNF alpha-induced protein 4; ligand of eph-related kinase 1; immediate early response protein B61; eph-related receptor tyrosine kinase ligand 1; tumor necrosis factor alpha-induced protein 4; tumor necrosis factor, alpha-induced protein 4; B61; EFL1; EPLG1; LERK-1; TNFAIP4;
Gene ID : 1942
mRNA Refseq : NM_004428
Protein Refseq : NP_004419
MIM : 191164
UniProt ID : P20827

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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08/15/2019

    Their prompt assistance and willingness to go above and beyond to ensure my success have been immensely valuable.

    04/04/2019

      Its purity, stability, and consistency are unparalleled, ensuring reliable and reproducible results in my research.

      11/22/2016

        This protein has proven to be an invaluable asset in my experiments, enabling accurate and precise measurements with exceptional sensitivity.

        Q&As (5)

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        Can EFNA1 be a target for therapeutic interventions in cancer treatment? 05/06/2021

        Yes, EFNA1 is being investigated as a potential therapeutic target in cancer treatment, aiming to develop drugs that modulate its activity.

        Are there diagnostic applications for EFNA1 in cancer detection? 01/15/2021

        Researchers are exploring the use of EFNA1 as a biomarker for cancer detection, with studies suggesting its potential as a diagnostic tool.

        How does EFNA1 interact with the Eph receptors, and what is the significance of this interaction? 04/16/2019

        EFNA1 binds to Eph receptors, initiating cell signaling pathways that regulate various cellular processes, making this interaction crucial for normal physiological functions.

        How does EFNA1 impact cancer research and treatment? 02/02/2018

        EFNA1 is implicated in cancer progression, influencing cell migration and invasion. Understanding its role can potentially lead to targeted therapies for certain cancers.

        Are there any neurological disorders associated with EFNA1 dysregulation? 10/26/2016

        Dysregulation of EFNA1 has been linked to certain neurological disorders, including Alzheimer's disease and neurodevelopmental disorders.

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