Active Recombinant Mouse Il27ra Protein, Fc Chimera Il27ra-1013M

Active Recombinant Mouse Il27ra Protein, Fc Chimera


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Cat.No. : Il27ra-1013M Optional Service: Optional requirements on this protein
Product Overview : Recombinant Mouse Il27ra (Accession # O70394), fused with , was produced in Mouse myeloma cell line, NS0-derived.
Source : Mammalian cells
Species : Mouse
Tag : Fc
Predicted N Terminal : Gly29
Form : Lyophilized from a 0.2 µm filtered solution in PBS.
Bio-activity : Measured by its ability to inhibit IL-27-induced proliferation of mouse CD4+ T cells.The ED50 for this effect is typically 1-4 µg/mL in the presence of 10 ng/mL of recombinant mouse IL-27.Measured by its ability to inhibit IL-27 anti-viral activity using HepG2 human hepatocellular carcinoma cells infected with encephalomyocarditis (EMC) virus. Bender H. et al. (2009) Hepatology 50:585.The ED50 for this effect is typically 2-12 µg/mL.
Molecular Mass : Recombinant Mouse Il27ra, Fc Chimera has a calculated MW of 80 kDa (monomer). In SDS-PAGE migrates as 105-115 kDa, reducing conditions.
Purity : >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Reconstitution : Reconstitute at 100 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Gene Name : Il27ra interleukin 27 receptor, alpha [ Mus musculus ]
Official Symbol : Il27ra
Synonyms : IL27RA; interleukin 27 receptor, alpha; interleukin-27 receptor subunit alpha; IL-27RA; IL-27R-alpha; IL-27R subunit alpha; T cell cytokine receptor; IL-27 receptor subunit alpha; type I T-cell cytokine receptor; cytokine receptor family, class 1 (WSXWS), member 1; CRL1; Tccr; Wsx1; WSX-1; IL-27R; zcytor1;
Gene ID : 50931
mRNA Refseq : NM_016671
Protein Refseq : NP_057880
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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