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Active Recombinant Mouse Il27ra Protein, Fc Chimera

Cat.No. : Il27ra-1013M
Product Overview : Recombinant Mouse Il27ra (Accession # O70394), fused with , was produced in Mouse myeloma cell line, NS0-derived.
  • Specification
  • Gene Information
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Source : Mammalian cells
Species : Mouse
Tag : Fc
Predicted N Terminal : Gly29
Form : Lyophilized from a 0.2 µm filtered solution in PBS.
Bio-activity : Measured by its ability to inhibit IL-27-induced proliferation of mouse CD4+ T cells.The ED50 for this effect is typically 1-4 µg/mL in the presence of 10 ng/mL of recombinant mouse IL-27.Measured by its ability to inhibit IL-27 anti-viral activity using HepG2 human hepatocellular carcinoma cells infected with encephalomyocarditis (EMC) virus. Bender H. et al. (2009) Hepatology 50:585.The ED50 for this effect is typically 2-12 µg/mL.
Molecular Mass : Recombinant Mouse Il27ra, Fc Chimera has a calculated MW of 80 kDa (monomer). In SDS-PAGE migrates as 105-115 kDa, reducing conditions.
Purity : >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Reconstitution : Reconstitute at 100 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Gene Name : Il27ra interleukin 27 receptor, alpha [ Mus musculus ]
Official Symbol : Il27ra
Synonyms : IL27RA; interleukin 27 receptor, alpha; interleukin-27 receptor subunit alpha; IL-27RA; IL-27R-alpha; IL-27R subunit alpha; T cell cytokine receptor; IL-27 receptor subunit alpha; type I T-cell cytokine receptor; cytokine receptor family, class 1 (WSXWS), member 1; CRL1; Tccr; Wsx1; WSX-1; IL-27R; zcytor1;
Gene ID : 50931
mRNA Refseq : NM_016671
Protein Refseq : NP_057880
MIM :

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the use of Il27ra? 07/02/2022

In general, Il27ra should be administered by subcutaneous injection. For specific use, follow your doctor's advice and read the drug label carefully.

What is the action mechanism of Il27ra? 02/10/2022

Il27ra regulates the function of immune cells by binding to its receptor, inhibiting inflammatory response and enhancing antiviral ability.

Does the clinical applications of Il27ra? 09/08/2020

It is mainly used in clinical treatment of immune-related diseases, such as tumors, autoimmune diseases and so on.

Can Il27ra be used with other drugs? 10/29/2019

It can be used in conjunction with other medications in certain cases, but be sure to inform your doctor about the medications you are using to avoid the possibility of drug interactions.

Can Il27ra be used in children? 09/27/2019

The use of Il27ra in children is not yet clear, please follow the guidance of your doctor.

What are the side effects of Il27ra? 08/19/2019

No significant side effects of recombinant Il27ra have been found, but common adverse reactions such as local reactions and anaphylaxis may occur.

Customer Reviews (3)

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Reviews
03/19/2022

    Good stability, stable structure, not easy to deteriorate.

    12/08/2021

      The preparation process is very convenient and suitable for novice operators.

      02/21/2020

        This method is highly sensitive and can detect small amounts of protein.

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