| Cat.No. : |
Il27ra-1013M
Optional Service: Optional requirements on this protein
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| Product Overview : |
Recombinant Mouse Il27ra (Accession # O70394), fused with , was produced in Mouse myeloma cell line, NS0-derived. |
| Source : |
Mammalian cells |
| Species : |
Mouse |
| Tag : |
Fc |
| Predicted N Terminal : |
Gly29 |
| Form : |
Lyophilized from a 0.2 µm filtered solution in PBS. |
| Bio-activity : |
Measured by its ability to inhibit IL-27-induced proliferation of mouse CD4+ T cells.The ED50 for this effect is typically 1-4 µg/mL in the presence of 10 ng/mL of recombinant mouse IL-27.Measured by its ability to inhibit IL-27 anti-viral activity using HepG2 human hepatocellular carcinoma cells infected with encephalomyocarditis (EMC) virus. Bender H. et al. (2009) Hepatology 50:585.The ED50 for this effect is typically 2-12 µg/mL. |
| Molecular Mass : |
Recombinant Mouse Il27ra, Fc Chimera has a calculated MW of 80 kDa (monomer). In SDS-PAGE migrates as 105-115 kDa, reducing conditions. |
| Purity : |
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
| Storage : |
Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC). |
| Reconstitution : |
Reconstitute at 100 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin. |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
