Active Recombinant Mouse Il27ra Protein, Fc Chimera
Cat.No. : | Il27ra-1013M |
Product Overview : | Recombinant Mouse Il27ra (Accession # O70394), fused with , was produced in Mouse myeloma cell line, NS0-derived. |
- Specification
- Gene Information
- Related Products
Source : | Mammalian cells |
Species : | Mouse |
Tag : | Fc |
Predicted N Terminal : | Gly29 |
Form : | Lyophilized from a 0.2 µm filtered solution in PBS. |
Bio-activity : | Measured by its ability to inhibit IL-27-induced proliferation of mouse CD4+ T cells.The ED50 for this effect is typically 1-4 µg/mL in the presence of 10 ng/mL of recombinant mouse IL-27.Measured by its ability to inhibit IL-27 anti-viral activity using HepG2 human hepatocellular carcinoma cells infected with encephalomyocarditis (EMC) virus. Bender H. et al. (2009) Hepatology 50:585.The ED50 for this effect is typically 2-12 µg/mL. |
Molecular Mass : | Recombinant Mouse Il27ra, Fc Chimera has a calculated MW of 80 kDa (monomer). In SDS-PAGE migrates as 105-115 kDa, reducing conditions. |
Purity : | >95%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
Storage : | Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC). |
Reconstitution : | Reconstitute at 100 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin. |
Gene Name : | Il27ra interleukin 27 receptor, alpha [ Mus musculus ] |
Official Symbol : | Il27ra |
Synonyms : | IL27RA; interleukin 27 receptor, alpha; interleukin-27 receptor subunit alpha; IL-27RA; IL-27R-alpha; IL-27R subunit alpha; T cell cytokine receptor; IL-27 receptor subunit alpha; type I T-cell cytokine receptor; cytokine receptor family, class 1 (WSXWS), member 1; CRL1; Tccr; Wsx1; WSX-1; IL-27R; zcytor1; |
Gene ID : | 50931 |
mRNA Refseq : | NM_016671 |
Protein Refseq : | NP_057880 |
MIM : |
Products Types
◆ Recombinant Protein | ||
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IL27RA-1928H | Recombinant Human IL27RA Protein, MYC/DDK-tagged | +Inquiry |
IL27RA-1174H | Recombinant Human IL27RA Protein, His (Fc)-Avi-tagged | +Inquiry |
IL27RA-228H | Active Recombinant Human IL27RA protein, C-His-tagged, 33-514 aa | +Inquiry |
◆ Lysates | ||
IL27RA-2909HCL | Recombinant Human IL27RA cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionIn general, Il27ra should be administered by subcutaneous injection. For specific use, follow your doctor's advice and read the drug label carefully.
Il27ra regulates the function of immune cells by binding to its receptor, inhibiting inflammatory response and enhancing antiviral ability.
It is mainly used in clinical treatment of immune-related diseases, such as tumors, autoimmune diseases and so on.
It can be used in conjunction with other medications in certain cases, but be sure to inform your doctor about the medications you are using to avoid the possibility of drug interactions.
The use of Il27ra in children is not yet clear, please follow the guidance of your doctor.
No significant side effects of recombinant Il27ra have been found, but common adverse reactions such as local reactions and anaphylaxis may occur.
Customer Reviews (3)
Write a reviewGood stability, stable structure, not easy to deteriorate.
The preparation process is very convenient and suitable for novice operators.
This method is highly sensitive and can detect small amounts of protein.
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